RECRUITING

Analgesia-First Sedation in Trauma Patients

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The study's aim is to ascertain the best approach for providing sedation and pain management for patients who have sustained trauma and are requiring respiratory support from a mechanical ventilator. The common approach to patients who need mechanical ventilation is to provide continuous drips of sedatives and pain medicine and awaken the patient once a day to check the brain functions. Another approach is to provide pain medicine and reserve sedatives for only a short duration when needed. The difference between approaches has not been studied in Trauma patients.

Official Title

Analgesia-First Sedation in Trauma Patients

Quick Facts

Study Start:2023-04-01
Study Completion:2025-09-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05751863

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. ≥ 18 years of age
  2. 2. Mechanically ventilated with an expected duration of MV ≥ 48h
  3. 3. Initiated continuous sedative/analgesic infusions by the ICU team
  4. 4. Patient is a candidate for MV weaning
  1. 1. Admission after resuscitation from cardiac arrest
  2. 2. Significant neurological deficit due to a chronic disorder
  3. 3. History of alcohol dependence and/or other illicit drug abuse
  4. 4. Prior administration of continuous sedative/analgesic from a transferring institution
  5. 5. Patient receiving neuromuscular blocking agents
  6. 6. Allergy to midazolam, lorazepam, and/or propofol

Contacts and Locations

Study Locations (Sites)

Long Beach Memorial Medical Center
Long Beach, California, 90806
United States

Collaborators and Investigators

Sponsor: MemorialCare Health System

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-04-01
Study Completion Date2025-09-01

Study Record Updates

Study Start Date2023-04-01
Study Completion Date2025-09-01

Terms related to this study

Keywords Provided by Researchers

  • Trauma
  • Analgesia
  • Sedation
  • Intubation

Additional Relevant MeSH Terms

  • Mechanical Ventilation
  • Respiratory Failure