RECRUITING

Hyperpolarized 129Xe MRI Lung Health Cohort

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

A subset of young adults participating in the American Lung Association (ALA) Lung Health Cohort (LHC) will be imaged using Hyperpolarized 129Xe MRI to assess lung structure and function. Images will be used to improve the understanding of lung health and early lung abnormalities that may lead to chronic lung disease.

Official Title

Hyperpolarized 129Xe MRI to Identify Structural Determinants of Low Lung Function and Respiratory Symptoms in Young Adults From the Lung Health Cohort

Quick Facts

Study Start:2023-11-30
Study Completion:2027-03-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05766384

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:25 Years to 35 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Is enrolled in the American Lung Association Lung Health Cohort Study.
  2. * Has completed CT imaging for the LHC study within 2 years of the scheduled Xe-MRI date.
  1. * Pacemaker, internal defibrillator or other implanted electronic devices or any standard MRI contraindications (e.g., claustrophobia, \> 140 cm shoulder circumference, dependent on weight distribution).
  2. * Is pregnant or breastfeeding
  3. * Oxygen saturation (SpO2) \<88% on room air or with supplemental oxygen.

Contacts and Locations

Study Contact

Cristal Monge
CONTACT
913-945-9399
chernandez@kumc.edu

Study Locations (Sites)

University of Illinois-Chicago
Chicago, Illinois, 60607
United States
University of Iowa
Iowa City, Iowa, 52242
United States
University of Kansas Medical Center
Kansas City, Kansas, 66160
United States
Duke University
Durham, North Carolina, 27708
United States
Baylor College of Medicine
Houston, Texas, 77030
United States
MD Anderson Cancer Center
Houston, Texas, 77030
United States

Collaborators and Investigators

Sponsor: University of Kansas Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-11-30
Study Completion Date2027-03-31

Study Record Updates

Study Start Date2023-11-30
Study Completion Date2027-03-31

Terms related to this study

Additional Relevant MeSH Terms

  • Healthy