Hyperpolarized 129Xe MRI Lung Health Cohort

Description

A subset of young adults participating in the American Lung Association (ALA) Lung Health Cohort (LHC) will be imaged using Hyperpolarized 129Xe MRI to assess lung structure and function. Images will be used to improve the understanding of lung health and early lung abnormalities that may lead to chronic lung disease.

Conditions

Healthy

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Study Overview

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Study Details

Study overview

A subset of young adults participating in the American Lung Association (ALA) Lung Health Cohort (LHC) will be imaged using Hyperpolarized 129Xe MRI to assess lung structure and function. Images will be used to improve the understanding of lung health and early lung abnormalities that may lead to chronic lung disease.

Hyperpolarized 129Xe MRI to Identify Structural Determinants of Low Lung Function and Respiratory Symptoms in Young Adults From the Lung Health Cohort

Hyperpolarized 129Xe MRI Lung Health Cohort

Condition
Healthy
Intervention / Treatment

-

Contacts and Locations

Chicago

University of Illinois-Chicago, Chicago, Illinois, United States, 60607

Iowa City

University of Iowa, Iowa City, Iowa, United States, 52242

Kansas City

University of Kansas Medical Center, Kansas City, Kansas, United States, 66160

Durham

Duke University, Durham, North Carolina, United States, 27708

Houston

Baylor College of Medicine, Houston, Texas, United States, 77030

Houston

MD Anderson Cancer Center, Houston, Texas, United States, 77030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Is enrolled in the American Lung Association Lung Health Cohort Study.
  • * Has completed CT imaging for the LHC study within 2 years of the scheduled Xe-MRI date.
  • * Pacemaker, internal defibrillator or other implanted electronic devices or any standard MRI contraindications (e.g., claustrophobia, \> 140 cm shoulder circumference, dependent on weight distribution).
  • * Is pregnant or breastfeeding
  • * Oxygen saturation (SpO2) \<88% on room air or with supplemental oxygen.

Ages Eligible for Study

25 Years to 35 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Kansas Medical Center,

Study Record Dates

2027-03-31