RECRUITING

Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure

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Conditions

Cold ExposureBrown fatFish oilCold

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This clinical trial will assess the whether fish oil supplementation can modulate brown fat activation, shivering, thermal comfort and skin blood flow during cold exposure.

Official Title

Omega-3 Fatty Acid Modulation of Brown Adipose Tissue for Arctic Resilience

Quick Facts

Study Start:2023-06-12
Study Completion:2024-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05822141

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 40 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Male and female, between the ages of 18 to 40 years.
  2. * Body Mass Index (BMI) of 18.5 to 24.9 kg/m2
  3. * Considered "moderately to highly active" by the International Physical Activity Questionnaire (IPAQ) and the Physical Activity Readiness Questionnaire (PAR-Q+)
  1. * History of smoking or recreational smoking, hyperlipidemia, hypertension/cardiovascular disease, diabetes, renal disease, neurological disease, metabolic disease, and bleeding disorders or delayed clotting time.
  2. * Taking SSRI's (antidepressants and anxiety medication), ADD/ADHD medication, and chronically consume pain medication (Aleve, Tylenol, CBD, etc).
  3. * Have or have had chronic disorders of the rectum (e.g., cancer, surgery, active hemorrhoids, etc.) or who currently have related acute conditions (diarrhea, constipation, etc.).
  4. * Have or have had a diagnosis of disorders related to immune suppression and/or autoimmune disease.
  5. * Are pregnant or planning on being pregnant.
  6. * Resting blood pressure of \> 130mmHg systolic or 90 mmHg diastolic.
  7. * Resting Pulse rate of \> 100 bpm.
  8. * History of regularly consuming fish oil supplements and/or regularly eating more than one fish meal per week.
  9. * Consuming more than one fish meal per week during the study.

Contacts and Locations

Study Contact

Timothy D Mickleborough, PhD
CONTACT
812-855-0753
tmickleb@indiana.edu
Abigail S Sogard, B.S.
CONTACT
asogard@iu.edu

Principal Investigator

Timothy D Mickleborough, PhD
PRINCIPAL_INVESTIGATOR
Indiana University

Study Locations (Sites)

Human Perfromance Lab, Indiana University
Bloomington, Indiana, 47405
United States

Collaborators and Investigators

Sponsor: Indiana University

  • Timothy D Mickleborough, PhD, PRINCIPAL_INVESTIGATOR, Indiana University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-06-12
Study Completion Date2024-12

Study Record Updates

Study Start Date2023-06-12
Study Completion Date2024-12

Terms related to this study

Keywords Provided by Researchers

  • Brown fat
  • Fish oil
  • Cold

Additional Relevant MeSH Terms

  • Cold Exposure