RECRUITING

Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to learn if there is a difference in morphine requirements in patients after upper extremity surgeries including shoulder arthroscopy. The main question it aims to answer is whether there is a difference between Interscalene brachial plexus blocks with the addition of buprenorphine, dexamethasone, and clonidine and the same block without the adjuvant.

Official Title

Effects of a Triple Adjuvant Combination of Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery, a Prospective, Randomized Clinical Trial

Quick Facts

Study Start:2023-02-28
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05824832

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients ≥ 18 years old
  2. * Patients undergoing shoulder arthroscopy
  3. * Patients willing to participate and sign informed consent
  1. * Severe COPD/other contraindication to general anesthesia
  2. * Patient with a weight of less than 60 kg
  3. * Dementia, not alert or oriented to person, place, or time
  4. * Chronic pain patient with daily opioid use at home.
  5. * Patient with allergy to local anesthetics
  6. * Patient refusal
  7. * Total shoulder arthroplasty
  8. * Concomitant pain in different area from operative site.
  9. * Pregnancy
  10. * Patient with active infection on the injection sites for the blocks
  11. * Patients unable or willing to understand or comply with the study protocol

Contacts and Locations

Study Contact

Susan Fargo
CONTACT
708-216-8046
sfargo@luc.edu

Principal Investigator

Audrice Francois, MD
PRINCIPAL_INVESTIGATOR
Loyola University Chicago

Study Locations (Sites)

Loyola University Chicago
Maywood, Illinois, 60153
United States

Collaborators and Investigators

Sponsor: Loyola University

  • Audrice Francois, MD, PRINCIPAL_INVESTIGATOR, Loyola University Chicago

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-02-28
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2023-02-28
Study Completion Date2025-06-30

Terms related to this study

Keywords Provided by Researchers

  • buprenorphine
  • clonidine
  • dexamethasone
  • brachial plexus blocks
  • pain
  • shoulder
  • surgery

Additional Relevant MeSH Terms

  • Pain, Postoperative