Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery

Description

The goal of this clinical trial is to learn if there is a difference in morphine requirements in patients after upper extremity surgeries including shoulder arthroscopy. The main question it aims to answer is whether there is a difference between Interscalene brachial plexus blocks with the addition of buprenorphine, dexamethasone, and clonidine and the same block without the adjuvant.

Conditions

Pain, Postoperative

Talk to us

Study Overview

On this page

Study Details

Study overview

The goal of this clinical trial is to learn if there is a difference in morphine requirements in patients after upper extremity surgeries including shoulder arthroscopy. The main question it aims to answer is whether there is a difference between Interscalene brachial plexus blocks with the addition of buprenorphine, dexamethasone, and clonidine and the same block without the adjuvant.

Effects of a Triple Adjuvant Combination of Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery, a Prospective, Randomized Clinical Trial

Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery

Condition
Pain, Postoperative
Intervention / Treatment

-

Contacts and Locations

Maywood

Loyola University Chicago, Maywood, Illinois, United States, 60153

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients ≥ 18 years old
  • * Patients undergoing shoulder arthroscopy
  • * Patients willing to participate and sign informed consent
  • * Severe COPD/other contraindication to general anesthesia
  • * Patient with a weight of less than 60 kg
  • * Dementia, not alert or oriented to person, place, or time
  • * Chronic pain patient with daily opioid use at home.
  • * Patient with allergy to local anesthetics
  • * Patient refusal
  • * Total shoulder arthroplasty
  • * Concomitant pain in different area from operative site.
  • * Pregnancy
  • * Patient with active infection on the injection sites for the blocks
  • * Patients unable or willing to understand or comply with the study protocol

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Loyola University,

Audrice Francois, MD, PRINCIPAL_INVESTIGATOR, Loyola University Chicago

Study Record Dates

2025-06-30