RECRUITING

HIIT Effects on Cardiometabolic Health

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The primary aim of this randomized clinical trial is to compare the effects of three different HIIT protocols and a control group on cardiometabolic health in young adults with obesity. Participants will be randomly assigned to one of the following three groups, with each having varying work-to-rest ratios: 1) HIIT-A, 2) HIIT-B, 3) HIIT-C, and 4) control group. HIIT-A, HIIT-B, and HIIT-C groups will participate in six sessions of a running based HIIT program over a 2-week training period. Pre-clinical markers of cardiovascular disease, blood lipids and fasting glucose will be measured at the following three time points: baseline, post-intervention, and 2 weeks after the training cessation (i.e., measure for detraining effect). All measurements will be performed three days before the training program and three days after the intervention to avoid the effect of the last training session. Afterwards, the detraining test will be measured 2 weeks post intervention.

Official Title

Detraining Effect of Short-term HIIT on Cardiometabolic Risk in Young Adults With Obesity

Quick Facts

Study Start:2023-02-10
Study Completion:2024-12-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05838950

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 25 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Young adults with obesity (Age 18 to 25 years old, BMI ≥ 30 kg/m2).
  1. * Syndromic obesity; 1) Any clinical symptoms including cognitive delay, 2) abnormalities in body structure(s), 3) organ-specific abnormalities (kidney, liver failure, excessive eating, and/or other signs of hypothalamic dysfunction such as fatigue, weakness and/or lack of interest in activities.
  2. * Taking weight loss medication(s)
  3. * Currently enrolled (or within previous 6 months) in a weight loss program;
  4. * An underlying disease/medications (steroids, second generation psychotropic agents, hormonal contraception, statins, antihypertensive and antidiabetic medications) that could influence carbohydrate or lipid metabolism.
  5. * Presence of cardiac pacemaker.
  6. * Current or anticipated participation in another research that would interfere with any of the outcomes.
  7. * Current or anticipated pregnancy.

Contacts and Locations

Study Contact

Myong Won Seo, Ph.D
CONTACT
3154012723
mseo04@syr.edu
Wonhee Cho, MS
CONTACT
6267270270
mseo04@syr.edu

Principal Investigator

Joon Young Kim, Ph.D
PRINCIPAL_INVESTIGATOR
Syracuse University, Departments of Exercise Science

Study Locations (Sites)

Women's Building
Syracuse, New York, 13244
United States

Collaborators and Investigators

Sponsor: Syracuse University

  • Joon Young Kim, Ph.D, PRINCIPAL_INVESTIGATOR, Syracuse University, Departments of Exercise Science

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-02-10
Study Completion Date2024-12-10

Study Record Updates

Study Start Date2023-02-10
Study Completion Date2024-12-10

Terms related to this study

Keywords Provided by Researchers

  • HIIT
  • Detraining effects
  • Cardiometabolic disease
  • Obesity
  • Young adults

Additional Relevant MeSH Terms

  • Obesity
  • Cardiovascular Diseases
  • Metabolic Disease
  • High-intensity Interval Training