HIIT Effects on Cardiometabolic Health

Description

The primary aim of this randomized clinical trial is to compare the effects of three different HIIT protocols and a control group on cardiometabolic health in young adults with obesity. Participants will be randomly assigned to one of the following three groups, with each having varying work-to-rest ratios: 1) HIIT-A, 2) HIIT-B, 3) HIIT-C, and 4) control group. HIIT-A, HIIT-B, and HIIT-C groups will participate in six sessions of a running based HIIT program over a 2-week training period. Pre-clinical markers of cardiovascular disease, blood lipids and fasting glucose will be measured at the following three time points: baseline, post-intervention, and 2 weeks after the training cessation (i.e., measure for detraining effect). All measurements will be performed three days before the training program and three days after the intervention to avoid the effect of the last training session. Afterwards, the detraining test will be measured 2 weeks post intervention.

Conditions

Obesity, Cardiovascular Diseases, Metabolic Disease, High-intensity Interval Training

Talk to us

Study Overview

On this page

Study Details

Study overview

The primary aim of this randomized clinical trial is to compare the effects of three different HIIT protocols and a control group on cardiometabolic health in young adults with obesity. Participants will be randomly assigned to one of the following three groups, with each having varying work-to-rest ratios: 1) HIIT-A, 2) HIIT-B, 3) HIIT-C, and 4) control group. HIIT-A, HIIT-B, and HIIT-C groups will participate in six sessions of a running based HIIT program over a 2-week training period. Pre-clinical markers of cardiovascular disease, blood lipids and fasting glucose will be measured at the following three time points: baseline, post-intervention, and 2 weeks after the training cessation (i.e., measure for detraining effect). All measurements will be performed three days before the training program and three days after the intervention to avoid the effect of the last training session. Afterwards, the detraining test will be measured 2 weeks post intervention.

Detraining Effect of Short-term HIIT on Cardiometabolic Risk in Young Adults With Obesity

HIIT Effects on Cardiometabolic Health

Condition
Obesity
Intervention / Treatment

-

Contacts and Locations

Syracuse

Women's Building, Syracuse, New York, United States, 13244

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Young adults with obesity (Age 18 to 25 years old, BMI ≥ 30 kg/m2).
  • * Syndromic obesity; 1) Any clinical symptoms including cognitive delay, 2) abnormalities in body structure(s), 3) organ-specific abnormalities (kidney, liver failure, excessive eating, and/or other signs of hypothalamic dysfunction such as fatigue, weakness and/or lack of interest in activities.
  • * Taking weight loss medication(s)
  • * Currently enrolled (or within previous 6 months) in a weight loss program;
  • * An underlying disease/medications (steroids, second generation psychotropic agents, hormonal contraception, statins, antihypertensive and antidiabetic medications) that could influence carbohydrate or lipid metabolism.
  • * Presence of cardiac pacemaker.
  • * Current or anticipated participation in another research that would interfere with any of the outcomes.
  • * Current or anticipated pregnancy.

Ages Eligible for Study

18 Years to 25 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Syracuse University,

Joon Young Kim, Ph.D, PRINCIPAL_INVESTIGATOR, Syracuse University, Departments of Exercise Science

Study Record Dates

2024-12-10