COMPLETED

Ventilation and Esophageal Pressure Changes

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

A study to observe the effect of variations in ventilator settings including tidal volume and PEEP on transpulmonary pressure monitored with an esophageal balloon catheter and to correlate intraoperative transpulmonary pressure variations and intraoperative stroke volume variation changes.

Official Title

A Study of Intraoperative Transpulmonary and Intrathoracic Pressure Changes Associated With Ventilator Management of Tidal Volume and Positive End-expiratory Pressure (PEEP)

Quick Facts

Study Start:2022-06-16
Study Completion:2024-07-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT05859672

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients scheduled for elective surgery requiring general anesthesia and endotracheal intubation.
  2. * Age ≥ 18
  1. * Patients undergoing planned esophageal surgery
  2. * Patients with significant nasal or esophageal pathology
  3. * Adults unable to consent
  4. * Individuals who are not yet adults (infants, children, teenagers)
  5. * Pregnant women
  6. * Prisoners

Contacts and Locations

Principal Investigator

Neal Fleming, MD, PhD
PRINCIPAL_INVESTIGATOR
University of California, Davis

Study Locations (Sites)

UC Davis Medical Center
Sacramento, California, 95817
United States

Collaborators and Investigators

Sponsor: University of California, Davis

  • Neal Fleming, MD, PhD, PRINCIPAL_INVESTIGATOR, University of California, Davis

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-06-16
Study Completion Date2024-07-01

Study Record Updates

Study Start Date2022-06-16
Study Completion Date2024-07-01

Terms related to this study

Additional Relevant MeSH Terms

  • Mechanical Ventilation