RECRUITING

Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise

Description

The fluctuating concentrations of female sex hormones, namely estrogen and progesterone may have an effect on the ability of the tissue to withstand challenging exercise conditions, such as eccentric exercise. These sex hormones have also been purported to influence the perceived difficulty of exercise. This study aims to uncover how the different estrogen and progesterone concentrations present throughout the menstrual cycle effect perceived readiness to perform, perceptions of difficulty, and different recovery metrics.

Study Overview

Study Details

Study overview

The fluctuating concentrations of female sex hormones, namely estrogen and progesterone may have an effect on the ability of the tissue to withstand challenging exercise conditions, such as eccentric exercise. These sex hormones have also been purported to influence the perceived difficulty of exercise. This study aims to uncover how the different estrogen and progesterone concentrations present throughout the menstrual cycle effect perceived readiness to perform, perceptions of difficulty, and different recovery metrics.

Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise

Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise

Condition
Inflammatory Response
Intervention / Treatment

-

Contacts and Locations

Los Angeles

Clinical Exercise Research Center, Los Angeles, California, United States, 90033

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 18-35 years of age
  • * BMI of 18.5-29.9 as a BMI below or above these cut points results in highly varied menstrual cycle lengths \[15\]
  • * Not taking contraception or other types of medication that could influence reproductive status
  • * Regular menstruation
  • * Non-pregnant
  • * Medically free from chronic diseases
  • * Novel to downhill running
  • * Weight greater than or equal to 110 lbs
  • * Not taking exogenous hormones
  • * Not suffering from known gynecological disease (i.e., PCOS, endometriosis, etc.) that may influence menstrual cycle regularity
  • * Amenorrhea or oligomenorrhea
  • * Perimenopausal or menopausal
  • * Recreational or professional trail or downhill runner
  • * On a form of contraception
  • * Cardiac disability
  • * Pacemaker
  • * Arterial disease
  • * Uncontrolled hemorrhage
  • * Blood clots
  • * Pregnant or trying to become pregnant
  • * Cancerous lesions
  • * Sensory or mental impairment
  • * Unstable fractures
  • * Weight less than 110 lbs
  • * Suffering from gynecological disease (i.e., PCOS, endometriosis, etc.) that may influence menstrual cycle regularity
  • * Taking exogenous hormones

Ages Eligible for Study

18 Years to 35 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Southern California,

Study Record Dates

2026-08