RECRUITING

Aim 3 Particle Swarm Optimization PIGD

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

In Parkinson's disease (PD) patients undergoing standard-of-care Deep Brain Stimulation (DBS) therapy, to compare the effect on Parkinson's symptoms of two different neurostimulator settings designed to differ from each other as much as possible with respect to how much they activate two different neuroanatomical structures: the axonal pathway from Globus Pallidus (GP) to Pedunculopontine Nucleus (PPN), and the axonal pathway from PPN to GP.

Official Title

Aim 3 Particle Swarm Optimization Postural Instability Gait Disorder

Quick Facts

Study Start:2024-03-19
Study Completion:2027-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05934747

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * Inability to walk in the off-med, off-stimulation condition (even with safety harness)
  2. * Gait impaired significantly by a condition other than PD
  3. * Breaks or shorts in active contacts
  4. * IPG battery nearing end of life (in patients with primary-cell IPGs)
  5. * Females who are nursing or pregnant

Contacts and Locations

Study Contact

Scott Cooper, PhD, MD
CONTACT
612-626-9516
secooper@umn.edu

Study Locations (Sites)

University of Minnesota
Minneapolis, Minnesota, 55414
United States

Collaborators and Investigators

Sponsor: University of Minnesota

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-03-19
Study Completion Date2027-06-30

Study Record Updates

Study Start Date2024-03-19
Study Completion Date2027-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Parkinson's Disease and Parkinsonism