Aim 3 Particle Swarm Optimization PIGD

Description

In Parkinson's disease (PD) patients undergoing standard-of-care Deep Brain Stimulation (DBS) therapy, to compare the effect on Parkinson's symptoms of two different neurostimulator settings designed to differ from each other as much as possible with respect to how much they activate two different neuroanatomical structures: the axonal pathway from Globus Pallidus (GP) to Pedunculopontine Nucleus (PPN), and the axonal pathway from PPN to GP.

Conditions

Parkinson's Disease and Parkinsonism

Study Overview

Study Details

Study overview

In Parkinson's disease (PD) patients undergoing standard-of-care Deep Brain Stimulation (DBS) therapy, to compare the effect on Parkinson's symptoms of two different neurostimulator settings designed to differ from each other as much as possible with respect to how much they activate two different neuroanatomical structures: the axonal pathway from Globus Pallidus (GP) to Pedunculopontine Nucleus (PPN), and the axonal pathway from PPN to GP.

Aim 3 Particle Swarm Optimization Postural Instability Gait Disorder

Aim 3 Particle Swarm Optimization PIGD

Condition
Parkinson's Disease and Parkinsonism
Intervention / Treatment

-

Contacts and Locations

Minneapolis

University of Minnesota, Minneapolis, Minnesota, United States, 55414

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Inability to walk in the off-med, off-stimulation condition (even with safety harness)
  • * Gait impaired significantly by a condition other than PD
  • * Breaks or shorts in active contacts
  • * IPG battery nearing end of life (in patients with primary-cell IPGs)
  • * Females who are nursing or pregnant

Ages Eligible for Study

18 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Minnesota,

Study Record Dates

2027-06-30