RECRUITING

Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

Conditions

Gestational Diabetes Vascular Endothelial Function postpartum vascular

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this investigation is to examine the role of oxidative stress in aberrant microvascular function in otherwise healthy women with a history of GDM.

Official Title

Role of Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

Quick Facts

Study Start:2023-07-01

Study Completion:2027-06

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05946785

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 50 Years

Sexes Eligible for Study:FEMALE

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT

Inclusion Criteria	Exclusion Criteria
* female sex * 18 -50 years old * pregnancy history within 5 years of the study visit * had gestational diabetes diagnosed by their obstetrician and confirmed according to the American College of Obstetricians and Gynecologists criteria for gestational diabetes * or without a history of gestational diabetes	* skin diseases * current tobacco/e-cigarette use * diagnosed or suspected hepatic or metabolic disease including diabetes * statin or other cholesterol-lowering medication * current antihypertensive medication * history of preeclampsia or gestational hypertension * current pregnancy * body mass index \<18.5 kg/m2 * allergy to materials used during the experiment.(e.g. latex), known allergies to study drugs.

Inclusion Criteria

Exclusion Criteria

* female sex
* 18 -50 years old
* pregnancy history within 5 years of the study visit
* had gestational diabetes diagnosed by their obstetrician and confirmed according to the American College of Obstetricians and Gynecologists criteria for gestational diabetes
* or without a history of gestational diabetes

* skin diseases
* current tobacco/e-cigarette use
* diagnosed or suspected hepatic or metabolic disease including diabetes
* statin or other cholesterol-lowering medication
* current antihypertensive medication
* history of preeclampsia or gestational hypertension
* current pregnancy
* body mass index \<18.5 kg/m2
* allergy to materials used during the experiment.(e.g. latex), known allergies to study drugs.

Contacts and Locations

Study Contact

Anna Reid-Stanhewicz, PHD

CONTACT

319-467-1732

anna-stanhewicz@uiowa.edu

Study Locations (Sites)

University of Iowa

Iowa City, Iowa, 52242

United States

Collaborators and Investigators

Sponsor: Anna Stanhewicz, PhD

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-01

Study Completion Date2027-06

Study Record Updates

Study Start Date2023-07-01

Study Completion Date2027-06

Terms related to this study

Keywords Provided by Researchers

gestational diabetes
postpartum
vascular

Additional Relevant MeSH Terms

Gestational Diabetes
Vascular Endothelial Function