Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

Description

The purpose of this investigation is to examine the role of oxidative stress in aberrant microvascular function in otherwise healthy women with a history of GDM.

Conditions

Gestational Diabetes, Vascular Endothelial Function

Study Overview

Study Details

Study overview

The purpose of this investigation is to examine the role of oxidative stress in aberrant microvascular function in otherwise healthy women with a history of GDM.

Role of Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

Condition
Gestational Diabetes
Intervention / Treatment

-

Contacts and Locations

Iowa City

University of Iowa, Iowa City, Iowa, United States, 52242

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * female sex
  • * 18 -50 years old
  • * pregnancy history within 5 years of the study visit
  • * had gestational diabetes diagnosed by their obstetrician and confirmed according to the American College of Obstetricians and Gynecologists criteria for gestational diabetes
  • * or without a history of gestational diabetes
  • * skin diseases
  • * current tobacco/e-cigarette use
  • * diagnosed or suspected hepatic or metabolic disease including diabetes
  • * statin or other cholesterol-lowering medication
  • * current antihypertensive medication
  • * history of preeclampsia or gestational hypertension
  • * current pregnancy
  • * body mass index \<18.5 kg/m2
  • * allergy to materials used during the experiment.(e.g. latex), known allergies to study drugs.

Ages Eligible for Study

18 Years to 50 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Anna Stanhewicz, PhD,

Study Record Dates

2027-06