ACTIVE_NOT_RECRUITING

Couples Health Aging, Rhythms and Sleep Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Alzheimer's disease and related dementias (ADRD), including mild cognitive impairment (MCI), are becoming among the most prevalent causes of disability, death and healthcare costs worldwide. Sleep and circadian rhythm disturbances are common among individuals with MCI as well as their spouses/ partners and may increase risk of the development of ADRD in both patients and partners. This is the first study to systematically investigate sleep as a shared health behavior within couples in which one member has MCI, and the degree to which sleep and circadian disturbances impact both partners health and well-being, including cognitive decline and risk for ADRD.

Official Title

Couples Health Aging, Rhythms and Sleep Study (CHARMS Study)

Quick Facts

Study Start:2023-09-14
Study Completion:2027-10-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05952284

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Married or partnered in a romantic relationship, cohabiting for at least two years
  2. * age \>50
  3. * smartphone user
  4. * one partner meets criteria for cognitive impairment without severe impairment in daytime dysfunction according to telephone screening, while other partner must not meet this criteria for impairment.
  1. * Unstable or severe medical or psychiatric conditions that would interfere with study participation (including but not limited to current cancer treatment, psychosis, history of major stroke, head injury with loss of consciousness \>30 min, other neurologic/systemic illness that may affect cognition, alcohol or other substance abuse)
  2. * current use of antipsychotic or anticonvulsant medications
  3. * inadequate vision, hearing, or dexterity to participate in the assessment
  4. * night shift work \>1x per month (defined as beginning work after 9:00 pm or work in the overnight hours \[12:00 am-5:00 am\])

Contacts and Locations

Study Locations (Sites)

University of Utah
Salt Lake City, Utah, 84108
United States

Collaborators and Investigators

Sponsor: University of Utah

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-09-14
Study Completion Date2027-10-02

Study Record Updates

Study Start Date2023-09-14
Study Completion Date2027-10-02

Terms related to this study

Keywords Provided by Researchers

  • aging
  • memory
  • sleep
  • circadian rhythms

Additional Relevant MeSH Terms

  • Aging
  • Memory Loss