Couples Health Aging, Rhythms and Sleep Study

Description

Alzheimer's disease and related dementias (ADRD), including mild cognitive impairment (MCI), are becoming among the most prevalent causes of disability, death and healthcare costs worldwide. Sleep and circadian rhythm disturbances are common among individuals with MCI as well as their spouses/ partners and may increase risk of the development of ADRD in both patients and partners. This is the first study to systematically investigate sleep as a shared health behavior within couples in which one member has MCI, and the degree to which sleep and circadian disturbances impact both partners health and well-being, including cognitive decline and risk for ADRD.

Conditions

Aging, Memory Loss

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Study Overview

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Study Details

Study overview

Alzheimer's disease and related dementias (ADRD), including mild cognitive impairment (MCI), are becoming among the most prevalent causes of disability, death and healthcare costs worldwide. Sleep and circadian rhythm disturbances are common among individuals with MCI as well as their spouses/ partners and may increase risk of the development of ADRD in both patients and partners. This is the first study to systematically investigate sleep as a shared health behavior within couples in which one member has MCI, and the degree to which sleep and circadian disturbances impact both partners health and well-being, including cognitive decline and risk for ADRD.

Couples Health Aging, Rhythms and Sleep Study (CHARMS Study)

Couples Health Aging, Rhythms and Sleep Study

Condition
Aging
Intervention / Treatment

-

Contacts and Locations

Salt Lake City

University of Utah, Salt Lake City, Utah, United States, 84108

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Married or partnered in a romantic relationship, cohabiting for at least two years
  • * age \>50
  • * smartphone user
  • * one partner meets criteria for cognitive impairment without severe impairment in daytime dysfunction according to telephone screening, while other partner must not meet this criteria for impairment.
  • * Unstable or severe medical or psychiatric conditions that would interfere with study participation (including but not limited to current cancer treatment, psychosis, history of major stroke, head injury with loss of consciousness \>30 min, other neurologic/systemic illness that may affect cognition, alcohol or other substance abuse)
  • * current use of antipsychotic or anticonvulsant medications
  • * inadequate vision, hearing, or dexterity to participate in the assessment
  • * night shift work \>1x per month (defined as beginning work after 9:00 pm or work in the overnight hours \[12:00 am-5:00 am\])

Ages Eligible for Study

50 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Utah,

Study Record Dates

2027-10-02