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Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks

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Conditions

Pain, ChronicFacet Joint PainPain, ProceduralAnalgesialumbarmedial branch blockoffset analgesiaonset hyperalgesiaQSTquantitative sensory testing

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).

Official Title

OMEGA Study: Offset Mechanisms in Evaluation of Lumbar Medial Branch Block

Quick Facts

Study Start:2023-07-05
Study Completion:2025-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05961800

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Scheduled for lumbar MBB in UPMC Pain Management clinics
  2. * Age \> 18 years old
  3. * Predominantly axial chronic low back pain at least 3 months on a daily basis
  4. * Must meet the minimum criteria for cognitive function using the PROMIS 2-item cognitive screener (\>3)
  5. * Low back pain intensity of \> 3/10
  6. * Willing and able to receive study-related phone calls
  1. * History of spine surgery at the level of the lumbar MBB
  2. * Active worker's compensation or litigation claims
  3. * New pain and/or psychiatric treatments within 2 weeks of enrollment
  4. * Not fluent in English and/or not able to complete the questionnaires
  5. * Any clinically unstable systemic illness that is judged to interfere with the study

Contacts and Locations

Study Contact

Maya L Maurer, BS
CONTACT
412-665-8052
mam708@pitt.edu
Benedict J Alter, MD, PhD
CONTACT
412-677-0575
alterbj@upmc.edu

Principal Investigator

Benedict J Alter, MD, PhD
PRINCIPAL_INVESTIGATOR
University of Pittsburgh

Study Locations (Sites)

UPMC St. Margaret
Pittsburgh, Pennsylvania, 15215
United States

Collaborators and Investigators

Sponsor: University of Pittsburgh

  • Benedict J Alter, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-07-05
Study Completion Date2025-06

Study Record Updates

Study Start Date2023-07-05
Study Completion Date2025-06

Terms related to this study

Keywords Provided by Researchers

  • lumbar
  • medial branch block
  • offset analgesia
  • onset hyperalgesia
  • QST
  • quantitative sensory testing

Additional Relevant MeSH Terms

  • Pain, Chronic
  • Facet Joint Pain
  • Pain, Procedural
  • Analgesia