Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks

Description

This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).

Conditions

Pain, Chronic, Facet Joint Pain, Pain, Procedural, Analgesia

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Study Overview

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Study Details

Study overview

This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).

OMEGA Study: Offset Mechanisms in Evaluation of Lumbar Medial Branch Block

Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks

Condition
Pain, Chronic
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

UPMC St. Margaret, Pittsburgh, Pennsylvania, United States, 15215

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Scheduled for lumbar MBB in UPMC Pain Management clinics
  • * Age \> 18 years old
  • * Predominantly axial chronic low back pain at least 3 months on a daily basis
  • * Must meet the minimum criteria for cognitive function using the PROMIS 2-item cognitive screener (\>3)
  • * Low back pain intensity of \> 3/10
  • * Willing and able to receive study-related phone calls
  • * History of spine surgery at the level of the lumbar MBB
  • * Active worker's compensation or litigation claims
  • * New pain and/or psychiatric treatments within 2 weeks of enrollment
  • * Not fluent in English and/or not able to complete the questionnaires
  • * Any clinically unstable systemic illness that is judged to interfere with the study

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pittsburgh,

Benedict J Alter, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

2025-06