RECRUITING

Deconstructing Post Stroke Hemiparesis

Conditions

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

TRACTs (DeconsTructing Post StRoke HemipAresis for PreCision NeurorehabiliTation) is a single timepoint study that aims to deconstruct post-stroke deficits of the upper extremity into distinct components and relate these components to brain anatomy and physiology.

Official Title

Deconstructing Post Stroke Hemiparesis for Precision Neurorehabilitation

Quick Facts

Study Start:2023-09-05

Study Completion:2027-09

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05993221

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Not specified

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Diagnosis of a unilateral ischemic stroke occurring \>6 months prior as documented in medical chart * Upper extremity motor impairment as measured by Fugl-Meyer Upper Extremity Assessment ≤60 * Ability to follow simple instructions in English	* Greater than moderate difficulty using the arm and hand pre-dating the stroke as assessed by the questions adapted from the QuickDASH outcome measure score on any question \>= 3, which measures physical function and symptoms in people with difficulty using the arm and hand. * Visual or auditory disorders resulting in the inability to see or hear, respectively, the stimuli presented as part of research sessions * Inability to maintain a seated position for at least one hour * Standard MRI exclusion (e.g., significant claustrophobia or inability to tolerate loud noises, cardiac pacemaker (unless MRI-safe), implanted device (deep brain stimulation) or metal in the brain, cervical spinal cord, or upper thoracic spinal cord) * Standard (single-pulse) TMS exclusion which include (in addition to those listed for MRI) pregnancy/lactation/planning to become pregnant during the study, seizure disorder, and primary or secondary CNS tumors

Inclusion Criteria

Exclusion Criteria

* Diagnosis of a unilateral ischemic stroke occurring \>6 months prior as documented in medical chart
* Upper extremity motor impairment as measured by Fugl-Meyer Upper Extremity Assessment ≤60
* Ability to follow simple instructions in English

* Greater than moderate difficulty using the arm and hand pre-dating the stroke as assessed by the questions adapted from the QuickDASH outcome measure score on any question \>= 3, which measures physical function and symptoms in people with difficulty using the arm and hand.
* Visual or auditory disorders resulting in the inability to see or hear, respectively, the stimuli presented as part of research sessions
* Inability to maintain a seated position for at least one hour
* Standard MRI exclusion (e.g., significant claustrophobia or inability to tolerate loud noises, cardiac pacemaker (unless MRI-safe), implanted device (deep brain stimulation) or metal in the brain, cervical spinal cord, or upper thoracic spinal cord)
* Standard (single-pulse) TMS exclusion which include (in addition to those listed for MRI) pregnancy/lactation/planning to become pregnant during the study, seizure disorder, and primary or secondary CNS tumors

Contacts and Locations

Study Contact

Jennifer Hebert, BS

CONTACT

401-273-7100

jennifer.hebert@va.gov

Kelly Rishe, OT

CONTACT

401-273-7100

kelly.rishe@va.gov

Study Locations (Sites)

Providence VA Medical Center

Providence, Rhode Island, 02908

United States

Collaborators and Investigators

Sponsor: Providence VA Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-09-05

Study Completion Date2027-09

Study Record Updates

Study Start Date2023-09-05

Study Completion Date2027-09

Terms related to this study

Additional Relevant MeSH Terms

Stroke