Deconstructing Post Stroke Hemiparesis

Description

TRACTs (DeconsTructing Post StRoke HemipAresis for PreCision NeurorehabiliTation) is a single timepoint study that aims to deconstruct post-stroke deficits of the upper extremity into distinct components and relate these components to brain anatomy and physiology.

Conditions

Stroke

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Study Overview

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Study Details

Study overview

TRACTs (DeconsTructing Post StRoke HemipAresis for PreCision NeurorehabiliTation) is a single timepoint study that aims to deconstruct post-stroke deficits of the upper extremity into distinct components and relate these components to brain anatomy and physiology.

Deconstructing Post Stroke Hemiparesis for Precision Neurorehabilitation

Deconstructing Post Stroke Hemiparesis

Condition
Stroke
Intervention / Treatment

-

Contacts and Locations

Providence

Providence VA Medical Center, Providence, Rhode Island, United States, 02908

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosis of a unilateral ischemic stroke occurring \>6 months prior as documented in medical chart
  • * Upper extremity motor impairment as measured by Fugl-Meyer Upper Extremity Assessment ≤60
  • * Ability to follow simple instructions in English
  • * Greater than moderate difficulty using the arm and hand pre-dating the stroke as assessed by the questions adapted from the QuickDASH outcome measure score on any question \>= 3, which measures physical function and symptoms in people with difficulty using the arm and hand.
  • * Visual or auditory disorders resulting in the inability to see or hear, respectively, the stimuli presented as part of research sessions
  • * Inability to maintain a seated position for at least one hour
  • * Standard MRI exclusion (e.g., significant claustrophobia or inability to tolerate loud noises, cardiac pacemaker (unless MRI-safe), implanted device (deep brain stimulation) or metal in the brain, cervical spinal cord, or upper thoracic spinal cord)
  • * Standard (single-pulse) TMS exclusion which include (in addition to those listed for MRI) pregnancy/lactation/planning to become pregnant during the study, seizure disorder, and primary or secondary CNS tumors

Ages Eligible for Study

18 Years to 90 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Providence VA Medical Center,

Study Record Dates

2027-09