RECRUITING

Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 1

Conditions

Post-Traumatic Headache traumatic brain injury veteran VA Connecticut Healthcare System

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The acute and subacute sensations that occur on the scalp with injection of different concentrations of bupivacaine for grater occipital nerve blockade will be compared. Each Veteran participant will be randomized to receive three different concentrations, which will be injected one week apart each.

Official Title

Anesthetic Greater Occipital Nerve Blockade in Veterans With Post-Traumatic Headache: Sub-study 1

Quick Facts

Study Start:2024-01-26

Study Completion:2025-03-31

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06069791

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* United States Military Veterans within VA Connecticut Healthcare System * Chronic post-traumatic headache per ICHD-3 criteria (i.e., headaches are continuing to occur three months after the head injury) * At least two headache days per week * MRI brain scan completed within the past 3 months if chronic PTH for less than one year, within the past year if chronic PTH for less than 5 years, and within 5 years if chronic PTH for more than 10 years * Review of MRI and the medical record does not reveal another source for headache	* Skull defect * Other contraindication to bupivacaine 1. Allergy or adverse reaction (e.g., rash, cardiac effects) to amide anesthetics, such as lidocaine 2. Instruction from clinician to avoid amide anesthetics, such as lidocaine * Pregnant or lack of adequate birth control

Inclusion Criteria

Exclusion Criteria

* United States Military Veterans within VA Connecticut Healthcare System
* Chronic post-traumatic headache per ICHD-3 criteria (i.e., headaches are continuing to occur three months after the head injury)
* At least two headache days per week
* MRI brain scan completed within the past 3 months if chronic PTH for less than one year, within the past year if chronic PTH for less than 5 years, and within 5 years if chronic PTH for more than 10 years
* Review of MRI and the medical record does not reveal another source for headache

* Skull defect
* Other contraindication to bupivacaine
1. Allergy or adverse reaction (e.g., rash, cardiac effects) to amide anesthetics, such as lidocaine
2. Instruction from clinician to avoid amide anesthetics, such as lidocaine
* Pregnant or lack of adequate birth control

Contacts and Locations

Study Contact

Emmanuelle Schindler, MD, PhD

CONTACT

203-932-5711

emmanuelle.schindler@va.gov

Study Locations (Sites)

VA Connecticut Healthcare System

West Haven, Connecticut, 06516

United States

Collaborators and Investigators

Sponsor: Yale University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-01-26

Study Completion Date2025-03-31

Study Record Updates

Study Start Date2024-01-26

Study Completion Date2025-03-31

Terms related to this study

Keywords Provided by Researchers

traumatic brain injury
veteran
VA Connecticut Healthcare System

Additional Relevant MeSH Terms

Post-Traumatic Headache