Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 1

Description

The acute and subacute sensations that occur on the scalp with injection of different concentrations of bupivacaine for grater occipital nerve blockade will be compared. Each Veteran participant will be randomized to receive three different concentrations, which will be injected one week apart each.

Conditions

Post-Traumatic Headache

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Study Overview

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Study Details

Study overview

The acute and subacute sensations that occur on the scalp with injection of different concentrations of bupivacaine for grater occipital nerve blockade will be compared. Each Veteran participant will be randomized to receive three different concentrations, which will be injected one week apart each.

Anesthetic Greater Occipital Nerve Blockade in Veterans With Post-Traumatic Headache: Sub-study 1

Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 1

Condition
Post-Traumatic Headache
Intervention / Treatment

-

Contacts and Locations

West Haven

VA Connecticut Healthcare System, West Haven, Connecticut, United States, 06516

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * United States Military Veterans within VA Connecticut Healthcare System
  • * Chronic post-traumatic headache per ICHD-3 criteria (i.e., headaches are continuing to occur three months after the head injury)
  • * At least two headache days per week
  • * MRI brain scan completed within the past 3 months if chronic PTH for less than one year, within the past year if chronic PTH for less than 5 years, and within 5 years if chronic PTH for more than 10 years
  • * Review of MRI and the medical record does not reveal another source for headache
  • * Skull defect
  • * Other contraindication to bupivacaine
  • 1. Allergy or adverse reaction (e.g., rash, cardiac effects) to amide anesthetics, such as lidocaine
  • 2. Instruction from clinician to avoid amide anesthetics, such as lidocaine
  • * Pregnant or lack of adequate birth control

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Yale University,

Study Record Dates

2025-03-31