RECRUITING

Effect of Anti-inflammatory Diet in Osteoarthritis

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with Osteoarthritis, and the role of microbiome and circulating metabolites.

Official Title

An Evaluator-blinded Randomized Controlled Trial Study of the Effect of Anti-inflammatory Diet in Subjects With Osteoarthritis

Quick Facts

Study Start:2023-10-01
Study Completion:2026-01-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06080347

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Unilateral radiographic symptomatic KOA
  2. * No changes in therapy during the previous 3 months
  3. * Interested in dietary intervention and able to provide consent and attend follow-up visits
  1. * Previous knee surgery
  2. * Severe radiographic disease (KL grade 4)
  3. * Rheumatoid Arthritis
  4. * Any Abnormal blood values in the comprehensive metabolic panel test at screen (Abnormality will be defined based on standard reference ranges)
  5. * Use of corticosteroids and/or intra-articular injections during the preceding 3 months
  6. * Use of fish oils and glucosamine
  7. * Participation in a weight loss program in the preceding 6 months
  8. * Recent changes in physical activity levels
  9. * Regular smoking
  10. * Patients with food allergies
  11. * Patient with other medical conditions that will impair the ability to participate in a nutritional study
  12. * Plan to change systemic therapy
  13. * Patients unwilling to change dietary habits

Contacts and Locations

Study Contact

Monica Guma, M.D., PhD
CONTACT
8588226523
mguma@health.ucsd.edu

Study Locations (Sites)

University of California
San Diego, California, 92122
United States

Collaborators and Investigators

Sponsor: University of California, San Diego

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-10-01
Study Completion Date2026-01-01

Study Record Updates

Study Start Date2023-10-01
Study Completion Date2026-01-01

Terms related to this study

Additional Relevant MeSH Terms

  • Osteoarthritis, Knee