RECRUITING

SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models. In this study, we will use a novel technique, "SeeMe," to objectively assess the level of consciousness in patients suffering from comas following ABI. SeeMe is a program that quantifies total facial motion over time and compares the response after a spoken command (i.e. "open your eyes") to a pre-stimulus baseline.

Official Title

SeeMe: A Pilot Study Developing Predictive, Real-Time Consciousness Assessment Metrics Based on Facial Expression Changes

Quick Facts

Study Start:2019-06-16
Study Completion:2025-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06083441

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18 years old or older
  2. * Healthy Volunteers
  3. * Comatose patients (patients with a GCS \< 9) due to an acute brain injury (traumatic brain injury, spontaneous subarachnoid hemorrhage, severe meningoencephalitis, etc.)
  1. * A history of a neurologically debilitating disease (i.e., dementia, glioblastoma, Alzheimer's, multiple sclerosis, major vessel stroke, previous severe TBI, etc.)
  2. * Any other medical condition that, in the judgment of the investigator, makes participation in the study unsafe.
  3. * Pregnant subjects
  4. * Comatose patients without a legal authorized representative (LAR)
  5. * Prisoners or wards of the state
  6. * Persons who have not attained the legal age for consent to treatments or procedures

Contacts and Locations

Study Contact

Sima Mofakham, PhD
CONTACT
631-444-1278
sima.mofakham@stonybrookmedicine.edu
Charles Mikell, MD
CONTACT
631-444-7328
charles.mikell@stonybrookmedicine.edu

Principal Investigator

Sima Mofakham, PhD
PRINCIPAL_INVESTIGATOR
Stony Brook Medicine

Study Locations (Sites)

Stony Brook University Hospital
Stony Brook, New York, 11794
United States

Collaborators and Investigators

Sponsor: Stony Brook University

  • Sima Mofakham, PhD, PRINCIPAL_INVESTIGATOR, Stony Brook Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-06-16
Study Completion Date2025-08

Study Record Updates

Study Start Date2019-06-16
Study Completion Date2025-08

Terms related to this study

Keywords Provided by Researchers

  • Consciousness
  • Acute brain injury
  • Consciousness Recovery
  • Consciousness Measurement
  • Facial Motion Analysis
  • Microscopic movements
  • Traumatic Brain Injury

Additional Relevant MeSH Terms

  • Disorder of Consciousness
  • Consciousness, Loss of
  • Trauma, Brain
  • Traumatic Brain Injury
  • Acute Brain Injury