SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury

Description

Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models. In this study, we will use a novel technique, "SeeMe," to objectively assess the level of consciousness in patients suffering from comas following ABI. SeeMe is a program that quantifies total facial motion over time and compares the response after a spoken command (i.e. "open your eyes") to a pre-stimulus baseline.

Conditions

Disorder of Consciousness, Consciousness, Loss of, Trauma, Brain, Traumatic Brain Injury, Acute Brain Injury

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Study Overview

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Study Details

Study overview

Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models. In this study, we will use a novel technique, "SeeMe," to objectively assess the level of consciousness in patients suffering from comas following ABI. SeeMe is a program that quantifies total facial motion over time and compares the response after a spoken command (i.e. "open your eyes") to a pre-stimulus baseline.

SeeMe: A Pilot Study Developing Predictive, Real-Time Consciousness Assessment Metrics Based on Facial Expression Changes

SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury

Condition
Disorder of Consciousness
Intervention / Treatment

-

Contacts and Locations

Stony Brook

Stony Brook University Hospital, Stony Brook, New York, United States, 11794

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 18 years old or older
  • * Healthy Volunteers
  • * Comatose patients (patients with a GCS \< 9) due to an acute brain injury (traumatic brain injury, spontaneous subarachnoid hemorrhage, severe meningoencephalitis, etc.)
  • * A history of a neurologically debilitating disease (i.e., dementia, glioblastoma, Alzheimer's, multiple sclerosis, major vessel stroke, previous severe TBI, etc.)
  • * Any other medical condition that, in the judgment of the investigator, makes participation in the study unsafe.
  • * Pregnant subjects
  • * Comatose patients without a legal authorized representative (LAR)
  • * Prisoners or wards of the state
  • * Persons who have not attained the legal age for consent to treatments or procedures

Ages Eligible for Study

18 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Stony Brook University,

Sima Mofakham, PhD, PRINCIPAL_INVESTIGATOR, Stony Brook Medicine

Study Record Dates

2025-08