RECRUITING

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study satiety in healthy individuals. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn more about the role of the cerebellum in satiety.

Official Title

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

Quick Facts

Study Start:2024-12-05
Study Completion:2028-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06105164

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Healthy individuals aged 18 to 65
  2. * BMI of 20-35.0 kg/m2
  3. * Normal or corrected-to-normal vision
  4. * Good general health
  5. * Ability to understand and willingness to sign written informed consent document
  1. * Current and/or past medical conditions
  2. * Current and/or past eating disorder
  3. * On a restricted diet and/or taking weight loss medication(s)
  4. * History of bariatric surgery
  5. * Weight fluctuation \>3% in past 3 months
  6. * Recent history of illicit recreational drug abuse
  7. * Current nicotine use
  8. * Intellectual disability
  9. * Conditions that might result in increased risks of side effects or complications from TMS or MRI

Contacts and Locations

Study Contact

Laura Holsen, PhD
CONTACT
617-525-8772
lholsen@bwh.harvard.edu
Mark Halko, PhD
CONTACT
617-855-2415
mhalko@mclean.harvard.edu

Principal Investigator

Laura Holsen, PhD
PRINCIPAL_INVESTIGATOR
Brigham and Women's Hospital

Study Locations (Sites)

McLean Hospital
Belmont, Massachusetts, 02478
United States
Brigham and Women's Hospital
Boston, Massachusetts, 02120
United States

Collaborators and Investigators

Sponsor: Brigham and Women's Hospital

  • Laura Holsen, PhD, PRINCIPAL_INVESTIGATOR, Brigham and Women's Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-05
Study Completion Date2028-08

Study Record Updates

Study Start Date2024-12-05
Study Completion Date2028-08

Terms related to this study

Additional Relevant MeSH Terms

  • Appetitive Behavior
  • Obesity