RECRUITING

A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

To learn about the relationship between changes in pupil size and reactivity and the start of neurological side effects in patients after receiving CAR-T cell therapy.

Official Title

A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity

Quick Facts

Study Start:2024-02-08
Study Completion:2027-04-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06144151

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. 1. Patients who have already been administered CAR-T cell therapy.
  2. 2. The patient who is unwilling or unable to comply with the requirements of the study including being able to be assessed with pupillometer
  3. 3. Patient has a condition which places him at an unacceptable risk as determined by the investigator

Contacts and Locations

Study Contact

Ranjit Nair, MD
CONTACT
(713) 563-4354
rnair@mdanderson.org

Principal Investigator

Ranjit Nair, MD
PRINCIPAL_INVESTIGATOR
M.D. Anderson Cancer Center

Study Locations (Sites)

MD Anderson Cancer Center
Houston, Texas, 77030
United States

Collaborators and Investigators

Sponsor: M.D. Anderson Cancer Center

  • Ranjit Nair, MD, PRINCIPAL_INVESTIGATOR, M.D. Anderson Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-02-08
Study Completion Date2027-04-01

Study Record Updates

Study Start Date2024-02-08
Study Completion Date2027-04-01

Terms related to this study

Additional Relevant MeSH Terms

  • Neurotoxicity