A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity

Description

To learn about the relationship between changes in pupil size and reactivity and the start of neurological side effects in patients after receiving CAR-T cell therapy.

Conditions

Neurotoxicity

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Study Overview

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Study Details

Study overview

To learn about the relationship between changes in pupil size and reactivity and the start of neurological side effects in patients after receiving CAR-T cell therapy.

A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity

A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity

Condition
Neurotoxicity
Intervention / Treatment

-

Contacts and Locations

Houston

MD Anderson Cancer Center, Houston, Texas, United States, 77030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Patients who have already been administered CAR-T cell therapy.
  • 2. The patient who is unwilling or unable to comply with the requirements of the study including being able to be assessed with pupillometer
  • 3. Patient has a condition which places him at an unacceptable risk as determined by the investigator

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

M.D. Anderson Cancer Center,

Ranjit Nair, MD, PRINCIPAL_INVESTIGATOR, M.D. Anderson Cancer Center

Study Record Dates

2027-04-01