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MAAT For Young Adult Cancer Survivors

Description

The goal of this clinical trial is to pilot-test a modified version of telehealth-delivered Memory and Attention Adaption Training (MAAT) that is tailored to young adult childhood cancer survivors (ages 18-39; MAAT-YS) with cancer-related cognitive impairment (CRCI). MAAT-YS consists of 8 weekly visits (45-minutes in duration) and participants use a survivor workbook and complete homework between visits. Participants in this single-group pilot trial (N=9) will complete online self-report measures of cognitive symptoms, quality of life, treatment satisfaction and a brief online neuropsychological test battery at baseline and post-MAAT-YS timepoints.

Conditions

Cancer
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Related Conditions:

Cancer

Study Overview

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Study Details

Study overview

The goal of this clinical trial is to pilot-test a modified version of telehealth-delivered Memory and Attention Adaption Training (MAAT) that is tailored to young adult childhood cancer survivors (ages 18-39; MAAT-YS) with cancer-related cognitive impairment (CRCI). MAAT-YS consists of 8 weekly visits (45-minutes in duration) and participants use a survivor workbook and complete homework between visits. Participants in this single-group pilot trial (N=9) will complete online self-report measures of cognitive symptoms, quality of life, treatment satisfaction and a brief online neuropsychological test battery at baseline and post-MAAT-YS timepoints.

Modifying Memory and Attention Adaptation Training (MAAT) For Young Adult Childhood Cancer Survivors

MAAT For Young Adult Cancer Survivors

Condition
Cancer
Intervention / Treatment

-

Contacts and Locations

Indianapolis

Indiana University School of Medicine, Indianapolis, Indiana, United States, 46202

Pittsburgh

University of Pittsburgh School of Medicine/UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, United States, 15213

Memphis,

St. Jude Children's Research Hospital, Memphis,, Tennessee, United States, 38105-3678

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Adults aged 18-39
  • 2. Diagnosed prior to 18 years of age with non-CNS solid tumor or leukemia/lymphoma without known CNS involvement
  • 3. At least 1 year after completion of treatment including chemotherapy, cancer-free
  • 4. English fluent
  • 5. Memory or other cognitive problems attributed to cancer and/or cancer treatment
  • 6. Score of \<10 on the FACT-Cog Impact on Quality of Life Scale
  • 7. Willing to use telehealth with internet access
  • 8. Willing to provide informed consent to participation
  • 1. Severe non-cancer brain injury such as severe traumatic brain injury, stroke or toxic injury causing memory impairments;
  • 2. Currently meeting Diagnostic and Statistical Manual-5 (DSM-5) criteria for a severe psychiatric disorder, including substance abuse, mood, anxiety, or psychotic disorders, as assessed by the PRIME-MD;
  • 3. Scoring 3 or below on the 6-item cognitive screen designed to detect severe memory disorders;59
  • 4. Severe uncorrected sensory impairment (severe hearing or visual impairment).

Ages Eligible for Study

18 Years to 39 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pittsburgh,

Robert J Ferguson, PhD, PRINCIPAL_INVESTIGATOR, St. Jude Children's Research Hospital

Donna Posluszny, PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

2025-12-31