RECRUITING

MAAT For Young Adult Cancer Survivors

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to pilot-test a modified version of telehealth-delivered Memory and Attention Adaption Training (MAAT) that is tailored to young adult childhood cancer survivors (ages 18-39; MAAT-YS) with cancer-related cognitive impairment (CRCI). MAAT-YS consists of 8 weekly visits (45-minutes in duration) and participants use a survivor workbook and complete homework between visits. Participants in this single-group pilot trial (N=9) will complete online self-report measures of cognitive symptoms, quality of life, treatment satisfaction and a brief online neuropsychological test battery at baseline and post-MAAT-YS timepoints.

Official Title

Modifying Memory and Attention Adaptation Training (MAAT) For Young Adult Childhood Cancer Survivors

Quick Facts

Study Start:2025-02-12
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06150976

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 39 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Adults aged 18-39
  2. 2. Diagnosed prior to 18 years of age with non-CNS solid tumor or leukemia/lymphoma without known CNS involvement
  3. 3. At least 1 year after completion of treatment including chemotherapy, cancer-free
  4. 4. English fluent
  5. 5. Memory or other cognitive problems attributed to cancer and/or cancer treatment
  6. 6. Score of \<10 on the FACT-Cog Impact on Quality of Life Scale
  7. 7. Willing to use telehealth with internet access
  8. 8. Willing to provide informed consent to participation
  1. 1. Severe non-cancer brain injury such as severe traumatic brain injury, stroke or toxic injury causing memory impairments;
  2. 2. Currently meeting Diagnostic and Statistical Manual-5 (DSM-5) criteria for a severe psychiatric disorder, including substance abuse, mood, anxiety, or psychotic disorders, as assessed by the PRIME-MD;
  3. 3. Scoring 3 or below on the 6-item cognitive screen designed to detect severe memory disorders;59
  4. 4. Severe uncorrected sensory impairment (severe hearing or visual impairment).

Contacts and Locations

Study Contact

Chloe A Sinagra
CONTACT
412-623-5975
chloe.sinagra@pitt.edu

Principal Investigator

Robert J Ferguson, PhD
PRINCIPAL_INVESTIGATOR
St. Jude Children's Research Hospital
Donna Posluszny, PhD
PRINCIPAL_INVESTIGATOR
University of Pittsburgh

Study Locations (Sites)

Indiana University School of Medicine
Indianapolis, Indiana, 46202
United States
University of Pittsburgh School of Medicine/UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15213
United States
St. Jude Children's Research Hospital
Memphis,, Tennessee, 38105-3678
United States

Collaborators and Investigators

Sponsor: University of Pittsburgh

  • Robert J Ferguson, PhD, PRINCIPAL_INVESTIGATOR, St. Jude Children's Research Hospital
  • Donna Posluszny, PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-12
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2025-02-12
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • Cancer
  • cancer survivorship
  • cancer-related cognitive impairment
  • CRCI
  • Cognitive-behavioral therapy
  • Memory Attention and Adaptation Training

Additional Relevant MeSH Terms

  • Cancer