RECRUITING

Salivary Extracellular Vesicle Associated lncRNAs in Heart Failure (SEAL-HF)

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to determine the relationship between the levels of Ribonucleic acid (RNA) circulating molecules, including ones in extracellular vesicles from different organs in the blood and in the saliva of patients with Acute Decompensated Heart Failure (ADHF) and Chronic Heart Failure (CHF) to see if a new, non-invasive diagnostic test can be developed for heart failure exacerbation.

Official Title

Salivary Extracellular Vesicle Associated lncRNAs in Heart Failure (SEAL-HF)

Quick Facts

Study Start:2023-04-19
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06169540

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * Active pregnancy or lactation
  2. * Cardiac amyloidosis
  3. * Active malignancies

Contacts and Locations

Study Contact

Saumya Das, MD, PhD
CONTACT
617-724-4500
sdas@mgh.harvard.edu
Michail Spanos, MD
CONTACT
617-906-1584
mspanos1@mgh.harvard.edu

Principal Investigator

Saumya Das, MD, PhD
PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital
Michail Spanos, MD
STUDY_DIRECTOR
Massachusetts General Hospital

Study Locations (Sites)

Massachusetts General Hospital
Boston, Massachusetts, 02114
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

  • Saumya Das, MD, PhD, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital
  • Michail Spanos, MD, STUDY_DIRECTOR, Massachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-04-19
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2023-04-19
Study Completion Date2025-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • CHF
  • ADHF
  • Control