RECRUITING

Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation

Description

To learn how radiation treatment may affect your responses to vaccines against pneumonia.

Conditions

Pneumococcal VaccineEsophageal CancerLymphopeniaChemoradiation
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Related Conditions:

Pneumococcal VaccineEsophageal CancerLymphopeniaChemoradiation

Study Overview

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Study Details

Study overview

To learn how radiation treatment may affect your responses to vaccines against pneumonia.

Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation

Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation

Condition
Pneumococcal Vaccine
Intervention / Treatment

-

Contacts and Locations

Houston

MD Anderson Cancer Center, Houston, Texas, United States, 77030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Group 1A
  • 2. Group 1B
  • 3. Group 2A
  • 4. Group 2B
  • 5. Group 3
  • 6. All Groups
  • 1. Participants of all genders, races and nationalities will be solicited.
  • 2. Age \>18 years
  • 3. Ability to understand and the willingness to sign a written informed consent document.
  • * Participants with compromised immunologic responses due to an uncontrolled intercurrent immunodeficiency (e.g., Human immunodeficiency virus (HIV), X-linked agammaglobulinemia) or previous or current immune suppressive therapy
  • * Participants receiving intravenous immunoglobulin (IVIG) during the study or in the three months prior to study enrollment.
  • * Participants with psychiatric illness/social situations that would limit compliance with study requirements.
  • * Participants with previous pneumococcal vaccination
  • * Participants with severe allergy to any of the vaccine components

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

M.D. Anderson Cancer Center,

Steven H Lin, MD, PRINCIPAL_INVESTIGATOR, M.D. Anderson Cancer Center

Study Record Dates

2025-09-30