RECRUITING

Unlocking Movement Potential: Enhancing Parkinson's Disease Treatment With Robotic EksoSkeleton

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to see how well therapy with the Eksobionic Exoskeleton (Esko) works for people with Parkinson's disease (PWPD). Esko is a robotic device that provides high repetition and intensity training. The investigators will examine its impact on walking, balance, and quality of life before, during and after an eight-week intervention program. The results will lay the groundwork for future trials, potentially leading to long-term improvements in mobility and quality of life for PWPD.

Official Title

Utilization of Robotic EksoSkeleton to Achieve High Dosing, Intensity, and Complexity of Gait in Treatment of People With Parkinson's Disease

Quick Facts

Study Start:2024-06-04
Study Completion:2026-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06225830

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Physician diagnosed idiopathic Parkinson's disease
  2. 2. All Hoehn and Yahr (H\&Y) stages will be eligible for inclusion in the study
  3. 3. Able to consent to participation in the research study
  4. 4. Pt agreeable to participate in 45-60 minutes of high intensity (RPE 14-17 for 30 minutes) gait training/ physical therapy.
  5. 5. Sufficient upper extremity strength to use a front wheeled walker
  6. 6. Pt to have self- reported walking/balance deficits
  7. 7. Age: Over age 18
  8. 8. Must be able to tolerate at least 15 min upright
  9. 9. Weigh 220 pounds (100kg) or less
  10. 10. Approximately between 5'0" and 6'4" tall
  11. 11. Have near normal range of motion in hips, knees, and ankles "Can you stand up and straighten your knees even for just a second?" or "Can you lay flat and straighten your knees so there is no bend in the knee?"
  1. 1. Currently involved in another intervention study or physical therapy course of care
  2. 2. Concurrent neurological disease
  3. 3. Leg length discrepancy, self-reported.
  4. 4. Spinal instability
  5. 5. Unresolved deep vein thrombosis
  6. 6. Severe muscular or skeletal pain
  7. 7. Open skin ulcerations on buttocks or other body surfaces in contact with exoskeleton or harness
  8. 8. Pregnancy
  9. 9. Cognitive impairments - unable to follow 2 steps commands and communicate for pain or to stop session
  10. 10. Participant requires the assistance of more than one therapist to transfer safely.
  11. 11. Uncontrolled or severe orthostatic hypotension that limits standing tolerance; defined as sustained, symptomatic drops in systolic and diastolic blood pressure when moving from sitting to standing
  12. 12. Active heterotrophic ossification (HO), hip dysplasia or hip/knee axis abnormalities
  13. 13. Colostomy
  14. 14. History of long bone fractures secondary to osteoporosis
  15. 15. Unable to sustain current medication regimen. Participant reports change in Parkinson's Medication in the past week.
  16. 16. Any reason the therapist may deem as harmful to the participant to enroll or continue in the study

Contacts and Locations

Study Contact

Jacqueline Brown, DPT
CONTACT
215-663-6575
Jxb892@jefferson.edu
Kris Ferrara, DPT
CONTACT
215-663-6575
Kristopher.Ferrara@jefferson.edu

Principal Investigator

Jacqueline Brown, DPT
PRINCIPAL_INVESTIGATOR
Albert Einstein Healthcare Network

Study Locations (Sites)

Jefferson Moss-Magee Rehabilitation - Elkins Park
Elkins Park, Pennsylvania, 19027
United States

Collaborators and Investigators

Sponsor: Albert Einstein Healthcare Network

  • Jacqueline Brown, DPT, PRINCIPAL_INVESTIGATOR, Albert Einstein Healthcare Network

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-06-04
Study Completion Date2026-06

Study Record Updates

Study Start Date2024-06-04
Study Completion Date2026-06

Terms related to this study

Additional Relevant MeSH Terms

  • Parkinson Disease