RECRUITING

Multimodal Musical Stimulation for Healthy Neurocognitive Aging

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a Stage I randomized, sham-controlled trial on the effects of multimodal musical stimulation on working memory in aging. Neurologically healthy older and younger adults will be tested on working memory and electroencephalography in the first randomized controlled trial of music as a form of brain stimulation, with multimodal musical stimulation and control stimulation conditions. Results will test the causal role of oscillatory mechanisms of the brain on cognition, and will lay the groundwork to the first musical, neurophysiologically targeted, brain-stimulation device for reversing cognitive decline in aging.

Official Title

Multimodal Musical Stimulation for Healthy Neurocognitive Aging

Quick Facts

Study Start:2022-12-11
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06229093

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 95 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * normal or corrected-to-normal vision
  2. * no more than mild hearing loss
  3. * no recent history of neurological or psychiatric disorders, including mood disorders or use of medications that may affect cognition or responsiveness to music.
  1. * moderate or severe hearing loss (40+ dB)
  2. * visual impairment (including color blindness) that cannot be corrected with glasses or contacts
  3. * recently changed dosage of cholinesterase inhibitors or psychotropic medication
  4. * recent history of psychotic or schizophrenic episodes
  5. * major neurologic diagnosis or other condition that might impair cognition or confound assessments (dementia, ADRD; Parkinson's disease, stroke, brain injury, epilepsy, or recent cardiovascular or neurovascular event)
  6. * recent history of serious physical trauma or diagnosis of serious chronic health condition requiring medical treatment and monitoring .

Contacts and Locations

Study Contact

Psyche Loui, PhD
CONTACT
6173736588
p.loui@northeastern.edu

Principal Investigator

Psyche Loui, PhD
PRINCIPAL_INVESTIGATOR
Northeastern University

Study Locations (Sites)

Northeastern University
Boston, Massachusetts, 02115
United States

Collaborators and Investigators

Sponsor: Northeastern University

  • Psyche Loui, PhD, PRINCIPAL_INVESTIGATOR, Northeastern University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-12-11
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2022-12-11
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • Music

Additional Relevant MeSH Terms

  • Aging