RECRUITING

Alcohol After Bariatric Surgery 2

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this observational study is to learn how the body processes ingested alcohol and how alcohol affects mood and blood sugar in both men and women after undergoing sleeve gastrectomy. The main question\[s\]it aims to answer are: * Are there differences in the way that ingested alcohol is handled in men versus women after sleeve gastrectomy? * What is the consequence of drinking alcohol on an empty stomach versus after a meal on blood sugar control after undergoing sleeve gastrectomy? Participants will participate in two types of alcohol tests (alcohol given orally or administered intravenously) after not eating anything overnight or after having a meal. Researchers will compare men and women who underwent sleeve gastrectomy with men and women who had no surgery, are of similar age and body composition, and have similar alcohol intake patterns.

Official Title

Pharmacokinetics and Responses to Alcohol After Bariatric Surgery

Quick Facts

Study Start:2024-08
Study Completion:2028-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06257771

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 64 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Surgery groups:
  2. * Male and female, 21-64 yrs. of age
  3. * Drink at least 1 standard drink per month but no more than 7 per week (women or \> 14 for men)
  4. * Underwent SG surgery 1-5 years ago
  5. * Male and female who did not undergo bariatric surgery
  6. * Age , BMI, race , and alcohol pattern of consumption equivalent to participants in the SG surgery groups
  1. * For all groups (surgery and non-surgery groups)
  2. * Smoking or having quit smoking less than 2 months ago
  3. * Pregnant or breastfeeding
  4. * Taking any medications that might affect alcohol metabolism
  5. * Anemia
  6. * Gastritis, colitis, Crohn's Disease, malabsorptive diseases, inflammatory diseases, liver disease, kidney disease, cancer less than five years ago, stroke, or severe organ dysfunction
  7. * Body weight \>450 pounds (because of a limit on body composition machine)
  8. * Alcohol use disorder
  9. * Regular use of drugs with addiction potential or regular misuse of substances
  10. * Abnormality on EKG as determined by a study physician to present a safety risk

Contacts and Locations

Study Contact

Mariel Molina-Castro, BS
CONTACT
217-300-4709
marielm2@illinois.edu

Principal Investigator

Marta Y Pepino de Gruev, PhD
PRINCIPAL_INVESTIGATOR
University of Illinois at Urbana-Champaign

Study Locations (Sites)

University of Illinois at Urbana Champaign
Urbana, Illinois, 61801
United States

Collaborators and Investigators

Sponsor: University of Illinois at Urbana-Champaign

  • Marta Y Pepino de Gruev, PhD, PRINCIPAL_INVESTIGATOR, University of Illinois at Urbana-Champaign

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-08
Study Completion Date2028-08

Study Record Updates

Study Start Date2024-08
Study Completion Date2028-08

Terms related to this study

Keywords Provided by Researchers

  • Alcohol metabolism
  • Bariatric surgery
  • Hypoglycemia
  • Metabolic surgery

Additional Relevant MeSH Terms

  • Sleeve Gastrectomy