COMPLETED

Mepivacaine vs Bupivacaine Spinal Anesthesia for TKA

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is a prospective, double-blind prospective randomized controlled trial comparing mepivacaine and bupivacaine spinal anesthesia for same-day discharge readiness following a unilateral primary elective TKA procedure. Study data will be collected during the patient's hospital stay for their TKA procedure, and the primary outcome of same-day discharge readiness will be assessed the day of surgery. Patients will also be contacted at Day 3 post-op to assess for any complications, current level of pain, and pain medication utilization.

Official Title

Mepivacaine Versus Bupivacaine Spinal Anesthesia for Same Day Discharge Following Total Knee Arthroplasty

Quick Facts

Study Start:2024-02-16
Study Completion:2025-08-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT06291727

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patient is at least 18 years of age who are scheduled for a primary elective TKA.
  2. * Patient can ambulate at least 10 feet independently without human assistance.
  3. * Patient must be a candidate for same day discharge as determined by American Society of Anesthesiologists (ASA) Physical Status Classification I and II
  1. * Patients scheduled for bilateral TKAs
  2. * Contraindication to spinal anesthesia
  3. * Revision TKAs
  4. * Allergy or contraindication to NSAIDs (e.g. chronic anti-coagulant use)
  5. * Workers' Compensation patient
  6. * Type I Diabetes
  7. * Type II Diabetes requiring insulin medication.
  8. * Pre-operative narcotics use with the exception of tramadol.
  9. * Renal insufficiency (GFR \< 60) that may impact post-operative protocol
  10. * Cognitive deficiencies that prevent the patient from providing their own informed consent
  11. * Language barrier preventing completion of study forms in English

Contacts and Locations

Study Locations (Sites)

Prisma Health Patewood Hospital
Greenville, South Carolina, 29615
United States

Collaborators and Investigators

Sponsor: Prisma Health-Upstate

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-02-16
Study Completion Date2025-08-01

Study Record Updates

Study Start Date2024-02-16
Study Completion Date2025-08-01

Terms related to this study

Keywords Provided by Researchers

  • knee arthroplasty
  • spinal anesthesia
  • same day discharge
  • mepivacaine
  • bupivacaine

Additional Relevant MeSH Terms

  • Anesthesia, Spinal
  • Arthroplasty, Replacement, Knee