COMPLETED

Application of L-PRF in Periodontal Surgery

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The study will compare the clinical outcomes of the two procedures, open flap debridement (OFD) compared to open flap debridement with leukocyte and platelet-rich fibrin (L-PFR) as well as differences in patient postoperative pain perception.

Official Title

The Effect of Application of L-PRF in Periodontal Surgery on Clinical Parameters and Patient Related Outcome Measures: A Randomized, Controlled, Clinical Study.

Quick Facts

Study Start:2023-08-19
Study Completion:2025-12-16
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT06296498

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 89 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients between age 18 and 89
  2. * Patients needing open flap debridement procedures for periodontal disease in one or more teeth in the same arch bilaterally (split mouth)
  3. * Patients must be nonsmokers, former smokers, or current smokers who smoke \<10 cigarettes per day, by self-report
  4. * Female patients to include non- pregnant women of child-bearing potential.
  1. * Patients who disclose that they will not be able to cooperate with the follow-up schedule.
  2. * Patients who are mentally incompetent, prisoners, or pregnant (as obtained via chart review or self-report)
  3. * Pregnant women or women intending to become pregnant during the study period
  4. * Smokers who smoke \> 10 cigarettes per day

Contacts and Locations

Principal Investigator

Charles Powell, DDS, MS
PRINCIPAL_INVESTIGATOR
The University of Texas Health Science Center at San Antonio

Study Locations (Sites)

The University of Texas Health Science Center at San Antonio
San Antonio, Texas, 78229
United States

Collaborators and Investigators

Sponsor: The University of Texas Health Science Center at San Antonio

  • Charles Powell, DDS, MS, PRINCIPAL_INVESTIGATOR, The University of Texas Health Science Center at San Antonio

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-08-19
Study Completion Date2025-12-16

Study Record Updates

Study Start Date2023-08-19
Study Completion Date2025-12-16

Terms related to this study

Keywords Provided by Researchers

  • Open flap debridement
  • Periodontal surgery
  • Periodontal wound healing

Additional Relevant MeSH Terms

  • Periodontal Diseases