Application of L-PRF in Periodontal Surgery

Description

The study will compare the clinical outcomes of the two procedures, open flap debridement (OFD) compared to open flap debridement with leukocyte and platelet-rich fibrin (L-PFR) as well as differences in patient postoperative pain perception.

Conditions

Periodontal Diseases

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Study Overview

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Study Details

Study overview

The study will compare the clinical outcomes of the two procedures, open flap debridement (OFD) compared to open flap debridement with leukocyte and platelet-rich fibrin (L-PFR) as well as differences in patient postoperative pain perception.

The Effect of Application of L-PRF in Periodontal Surgery on Clinical Parameters and Patient Related Outcome Measures: A Randomized, Controlled, Clinical Study.

Application of L-PRF in Periodontal Surgery

Condition
Periodontal Diseases
Intervention / Treatment

-

Contacts and Locations

San Antonio

The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States, 78229

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients between age 18 and 89
  • * Patients needing open flap debridement procedures for periodontal disease in one or more teeth in the same arch bilaterally (split mouth)
  • * Patients must be nonsmokers, former smokers, or current smokers who smoke \<10 cigarettes per day, by self-report
  • * Female patients to include non- pregnant women of child-bearing potential.
  • * Patients who disclose that they will not be able to cooperate with the follow-up schedule.
  • * Patients who are mentally incompetent, prisoners, or pregnant (as obtained via chart review or self-report)
  • * Pregnant women or women intending to become pregnant during the study period
  • * Smokers who smoke \> 10 cigarettes per day

Ages Eligible for Study

18 Years to 89 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

The University of Texas Health Science Center at San Antonio,

Charles Powell, DDS, MS, PRINCIPAL_INVESTIGATOR, The University of Texas Health Science Center at San Antonio

Study Record Dates

2026-03