RECRUITING

The Acute T-Rex (Timing of Resistance Exercise) Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The primary aim of this study is to evaluate if a single bout of AM vs PM resistance exercise has different effects on insulin sensitivity and sleep. A randomized cross-over trial be used to compare resistance exercise at two different times of the day. Each condition will take place in a laboratory setting. Each condition will consist of exercise, overnight sleep, and oral glucose tolerance tests the following day. The AM exercise will occur \~1.5 hours after habitual wake, and PM exercise will occur \~11 hours after habitual wake. After a 2-6 week washout, participants will complete the other condition. The hypothesis is that PM exercise will be more beneficial than AM exercise in improving insulin sensitivity. This study could identify if there is a better time of day to perform resistance exercise to decrease risk of developing Type 2 Diabetes Mellitus.

Official Title

Timing (AM v PM) of Acute Resistance Exercise on Glycemic Control in Older Adults: The Acute T-Rex Study

Quick Facts

Study Start:2023-11-15
Study Completion:2024-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06366399

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years to 74 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Men and women, all ethnicities, 50-74 years; BMI ≥25 kg/m2 to \<45 kg/m2; weight stable (\<5% change in past 6 months); and generally healthy, and who are not meeting recommended activity guidelines for aerobic or resistance exercise.
  1. * Uncontrolled cardiovascular, metabolic, renal, or pulmonary disease; cancer treatment in the past 5 years; untreated thyroid disease or other medical condition affecting weight or energy metabolism; current use of weight loss medication or other medications highly likely to impact energy balance; bariatric surgery or extensive bowel resection in past 2 years; current or recent history (past 2 years) of eating disorder; Diagnosis of insomnia, sleep apnea, or other sleep and circadian disorders; non-english speaking. HbA1c \>6.5%

Contacts and Locations

Study Contact

Tanya M Halliday, PhD
CONTACT
801-213-1364
tanya.halliday@utah.edu
Study Email Study Email
CONTACT
8014487897
trexstudy@utah.edu

Study Locations (Sites)

University of Utah HPER E Buildling
Salt Lake City, Utah, 84112
United States

Collaborators and Investigators

Sponsor: University of Utah

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-11-15
Study Completion Date2024-12-31

Study Record Updates

Study Start Date2023-11-15
Study Completion Date2024-12-31

Terms related to this study

Keywords Provided by Researchers

  • Resistance Exercise
  • Strength-training
  • Sleep
  • Circadian Rhythm

Additional Relevant MeSH Terms

  • Diabetes Mellitus, Type 2
  • Insulin Resistance
  • Glucose Intolerance
  • Sleep Disturbance
  • Overweight or Obesity
  • Insulin Sensitivity