RECRUITING

Intravenous Iron Versus Oral Iron for the Treatment of Iron Deficiency Anemia

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study aims to assess whether administering intravenous iron early in pregnancy, compared to standard oral iron treatment, can enhance hemoglobin levels before delivery and reduce the need for blood transfusions in patients with iron deficiency anemia. Patients diagnosed with iron deficiency anemia were randomly assigned to receive either oral or intravenous iron. Before treatment initiation, patients completed a symptom questionnaire baseline hemoglobin, and ferritin levels were measured. Follow-up visits occurred four weeks later and at 24 to 28 weeks gestation, involving reassessment of symptoms, laboratory testing, and monitoring of treatment adherence. Final hemoglobin levels were determined before delivery, and data on the need for blood transfusion at delivery were recorded.

Official Title

Randomized Control Trial: Intravenous Iron Versus Oral Iron for the Treatment of Iron Deficiency Anemia in Pregnancy

Quick Facts

Study Start:2023-11-21
Study Completion:2025-12-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06366698

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age \> 18 years of age
  2. * Ferritin level \< 30 ng/mL
  3. * Singe gestation
  4. * Gestational age up to 36 weeks as iron therapy after this has shown to be not beneficial at time of delivery. We will still plan to treat patients \> 36 weeks but not include them in the final analysis
  5. * Plan to delivery at Arrowhead Regional Medical Center (ARMC)
  1. * Maternal age \< 18 years of age
  2. * Incarcerated patients
  3. * Multifetal gestation
  4. * Acute liver/kidney disease
  5. * Active infections
  6. * Known hematological malignancy
  7. * Other causes of anemia such as alpha/beta thalassemia, sickle cell disease, Folate/B12 deficiency, and anemia of chronic diseases
  8. * Known hypersensitivity with IV iron
  9. * Severe symptoms of anemia requiring blood transfusion

Contacts and Locations

Study Locations (Sites)

Arrowhead Regional Medical Center
Colton, California, 92324
United States

Collaborators and Investigators

Sponsor: Arrowhead Regional Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-11-21
Study Completion Date2025-12-30

Study Record Updates

Study Start Date2023-11-21
Study Completion Date2025-12-30

Terms related to this study

Keywords Provided by Researchers

  • Anemia
  • Iron deficiency
  • Pregnancy
  • Intravenous iron

Additional Relevant MeSH Terms

  • Iron Deficiency Anemia of Pregnancy