RECRUITING

Effectiveness of Cognitive Training in Older and Younger Adults

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Conditions

Cognitive ChangeCognitive TrainingTraining taskTesting context

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The proposed study will enroll 1600 participants to examine the effectiveness of cognitive training. Participants will be randomized into different experimental groups and can expect to participate for up to 15 hours of research over 4 to 8 weeks.

Official Title

Examining the Effectiveness of Cognitive Training

Quick Facts

Study Start:2024-10-01
Study Completion:2028-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06375681

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Self-reported normal or corrected-to-normal vision
  2. * No known neurological impairments
  3. * Abnormal visual acuity prohibitive of training
  4. * History of seizures, focal brain lesion, or head injury with loss of consciousness in the past year
  5. * Physical handicap (motor or perceptual) that would impede training procedures
  6. * Medical illness requiring treatment during the study timeline
  7. * Social, educational or economic hardship prohibitive to training schedule
  8. * Concurrent enrollment in other cognitive training studies
  9. * History of major psychiatric illness, including psychosis, bipolar disorder, alcohol or substance abuse, recent bereavement
  10. * Score of 5 or more (i.e. presence of mild, moderate, or severe depression) on the Patient Health Screening Questionnaire (PHQ-9 Depression Screening); any participants reporting suicidal tendencies will be immediately referred to the site-specific Emergency Psychiatry Services (24-hour availability), and those with high depressive symptoms will be referred to their personal physician
  11. * Current alcohol consumption that exceeds 14 drinks per week
  12. * Illicit drug use
  13. * Plans to travel out of the area for more than 1 week during the intervention period
  14. * Residence too far from the testing site, which would prevent attending the testing sessions (\> 60 miles)
  15. * Not being proficient enough in English that would prevent following and understanding all instructions and completing all testing sessions (typically, participants would need to have learned English before age 11; there might be some exceptions that will be decided on a case-by-case basis).
  16. * Diagnosis of dementia or other neurological disease, including mild cognitive impairment (MCI)
  17. * Score \< 26 (out of 30) on the Mini Mental State Exam (MMSE)
  18. * Score \< 18 (out of 22) on the Telephone Montreal Cognitive Assessment (T-MoCA).
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

C. Shawn Green, PhD
CONTACT
(608) 263-4868
cshawn.green@wisc.edu
Freya Joessel, PhD
CONTACT
joessel@wisc.edu

Principal Investigator

Aaron R. Seitz, PhD
PRINCIPAL_INVESTIGATOR
University of California, Riverside
Susanne M. Jaeggi, PhD
PRINCIPAL_INVESTIGATOR
Northeastern University

Study Locations (Sites)

University of California, Riverside
Riverside, California, 92521
United States
Northeastern University
Boston, Massachusetts, 02115
United States
University of Wisconsin - Madison
Madison, Wisconsin, 53706
United States

Collaborators and Investigators

Sponsor: University of Wisconsin, Madison

  • Aaron R. Seitz, PhD, PRINCIPAL_INVESTIGATOR, University of California, Riverside
  • Susanne M. Jaeggi, PhD, PRINCIPAL_INVESTIGATOR, Northeastern University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-10-01
Study Completion Date2028-01

Study Record Updates

Study Start Date2024-10-01
Study Completion Date2028-01

Terms related to this study

Keywords Provided by Researchers

  • Cognitive Training
  • Training task
  • Testing context

Additional Relevant MeSH Terms

  • Cognitive Change