RECRUITING

Impact of Non-invasive Brain Stimulation on Learning Novel Spoken Words

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the proposed study is to use transcranial magnetic stimulation (TMS) to evaluate a neurobiological model of spoken word learning in older youth. Specifically, it is hypothesized that: (1) inhibition of the left dorsal stream will impact subsequent learning, processing, and retention of phonologically similar pseudowords; (2) the impact of dorsal stream inhibition on word learning will be associated with baseline levels of variability in neural activity, indicative of underlying differences in cortical excitability.

Official Title

Evaluating the Impact of Non-Invasive Brain Stimulation on Learning and Consolidation of Phonologically Similar Novel Spoken Words

Quick Facts

Study Start:2024-01-01
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06387615

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:16 Years to 24 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Native English speaker (who is not fluent in any other language and does not identify as bilingual)
  2. * Normal or corrected to normal vision
  1. * Diagnosed with Autism Spectrum Disorder
  2. * Hearing deficits (\>25 decibels at 500+ Hz), visual deficits (\>20/40), serious emotional problems (e.g., severe, uncontrolled depression) and certain neurological conditions (e.g., uncontrolled seizure disorders)
  3. * Individuals with certain metals in their bodies or with certain health conditions. If an individual has braces on their teeth, a cardiac pacemaker; hearing aid; other metal in their body or eyes (which may include certain metallic-embedded tattoos), including but not limited to pins, screws, shrapnel, plates, dentures or other metal objects
  4. * Individuals taking certain medications that lower seizure threshold
  5. * Individuals with TMS Screening and Contraindication Forms which do not pass TMS Tech review
  6. * Individuals with MRI Screening and Contraindication Forms which do not pass MRI Tech review

Contacts and Locations

Study Contact

C.Nikki Arrington, PhD
CONTACT
404-385-8621
carrington3@gsu.edu

Study Locations (Sites)

Georgia State University/Georgia Tech Center for Advanced Brain Imaging (CABI)
Atlanta, Georgia, 30318
United States

Collaborators and Investigators

Sponsor: Georgia State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-01-01
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2024-01-01
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • word learning
  • consolidation
  • vocabulary
  • artificial lexicon
  • brain stimulation
  • transcranial magnetic stimulation

Additional Relevant MeSH Terms

  • Dyslexia
  • Dyslexia, Developmental
  • Learning; Developmental Disorder, Reading