Impact of Non-invasive Brain Stimulation on Learning Novel Spoken Words

Description

The purpose of the proposed study is to use transcranial magnetic stimulation (TMS) to evaluate a neurobiological model of spoken word learning in older youth. Specifically, it is hypothesized that: (1) inhibition of the left dorsal stream will impact subsequent learning, processing, and retention of phonologically similar pseudowords; (2) the impact of dorsal stream inhibition on word learning will be associated with baseline levels of variability in neural activity, indicative of underlying differences in cortical excitability.

Conditions

Dyslexia, Dyslexia, Developmental, Learning; Developmental Disorder, Reading

Study Overview

Study Details

Study overview

The purpose of the proposed study is to use transcranial magnetic stimulation (TMS) to evaluate a neurobiological model of spoken word learning in older youth. Specifically, it is hypothesized that: (1) inhibition of the left dorsal stream will impact subsequent learning, processing, and retention of phonologically similar pseudowords; (2) the impact of dorsal stream inhibition on word learning will be associated with baseline levels of variability in neural activity, indicative of underlying differences in cortical excitability.

Evaluating the Impact of Non-Invasive Brain Stimulation on Learning and Consolidation of Phonologically Similar Novel Spoken Words

Impact of Non-invasive Brain Stimulation on Learning Novel Spoken Words

Condition
Dyslexia
Intervention / Treatment

-

Contacts and Locations

Atlanta

Georgia State University/Georgia Tech Center for Advanced Brain Imaging (CABI), Atlanta, Georgia, United States, 30318

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Native English speaker (who is not fluent in any other language and does not identify as bilingual)
  • * Normal or corrected to normal vision
  • * Diagnosed with Autism Spectrum Disorder
  • * Hearing deficits (\>25 decibels at 500+ Hz), visual deficits (\>20/40), serious emotional problems (e.g., severe, uncontrolled depression) and certain neurological conditions (e.g., uncontrolled seizure disorders)
  • * Individuals with certain metals in their bodies or with certain health conditions. If an individual has braces on their teeth, a cardiac pacemaker; hearing aid; other metal in their body or eyes (which may include certain metallic-embedded tattoos), including but not limited to pins, screws, shrapnel, plates, dentures or other metal objects
  • * Individuals taking certain medications that lower seizure threshold
  • * Individuals with TMS Screening and Contraindication Forms which do not pass TMS Tech review
  • * Individuals with MRI Screening and Contraindication Forms which do not pass MRI Tech review

Ages Eligible for Study

16 Years to 24 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Georgia State University,

Study Record Dates

2025-12-31