RECRUITING

Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Infections of the pleural space are common, and patients require antibiotics and chest drain placement to evacuate the chest from the infected fluid. Chest drains can get blocked by the drainage fluid and material. For this reason, it is thought that flushing the chest drain with saline solution, can help maintain the patency of the tube. This proposed study will evaluate the impact of regular chest drain flushing on the length of time to chest tube removal and total hospitalization as well as improvement in chest imaging and the need for additional interventions on the infected space.

Official Title

Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas

Quick Facts

Study Start:2024-06-21
Study Completion:2025-10-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06427538

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients with complicated parapneumonic pleural effusion and empyema requiring chest tube placement as standard of care for inpatient management of their pleural space infection with or without intrapleural tissue plasminogen activator and deoxyribonuclease therapy
  2. * Age \> 18 years old.
  1. * Patients who have surgical tubes that can't accommodate a three-way stopcock.
  2. * Study subject has any disease or condition that interferes with the safe completion of the study.
  3. * Inability to provide informed consent.
  4. * Inability to undergo a chest X-ray.
  5. * If the managing clinician believes the chest tube will be placed for less than 24 hours.
  6. * Patients with an indwelling pleural catheter (IPC)

Contacts and Locations

Study Contact

Samira Shojaee, MD, MPH
CONTACT
615-322-2386
samira.shojaee@vumc.org
Jennifer Duke, MD
CONTACT
615-322-2386
jennifer.duke@vumc.org

Principal Investigator

Jennifer D Duke, MD
STUDY_DIRECTOR
Vanderbilt University

Study Locations (Sites)

Vanderbilt University Medical Center
Nashville, Tennessee, 37203
United States

Collaborators and Investigators

Sponsor: Vanderbilt University Medical Center

  • Jennifer D Duke, MD, STUDY_DIRECTOR, Vanderbilt University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-06-21
Study Completion Date2025-10-30

Study Record Updates

Study Start Date2024-06-21
Study Completion Date2025-10-30

Terms related to this study

Keywords Provided by Researchers

  • empyema
  • pleural infection
  • chest tube
  • saline flush

Additional Relevant MeSH Terms

  • Empyema, Pleural
  • Pleural Infection