RECRUITING

The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to determine if the Fractionated Laser Resurfacing (FLR) procedure can protect one forearm/wrist from precancerous actinic keratosis (AKs) as well as prevent skin cancer in older subjects with active AKs. This study builds on a similar study ongoing at the Dayton Veterans Administration dermatology clinic. This study is also testing if a photograph of the skin can be used to predict where the AKs and an skin cancers will form.

Official Title

The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population

Quick Facts

Study Start:2024-03-20
Study Completion:2031-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06428721

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adult Males and Females aged 60 and older
  2. * Have at least 5 AKs on each forearm/wrist, but no more than 10 to allow for easy monitoring
  3. * Skin type fair (Fitzpatrick I-II)
  4. * Females must be post-menopausal and not be on systemic hormone replacement therapy
  5. * Able to comprehend procedures and risks
  1. * More than 10 AKs on an extremity
  2. * AKs that are large (2-3+, hyperkeratotic grade 3 lesions)
  3. * AKs that are very thick (\>3 mm)
  4. * Medical history of diabetes
  5. * History of poor wound healing or scarring
  6. * Large tattoos that can interfere with study
  7. * Other serious health issues and other skin diseases that could interfere with the study
  8. * Recent (within 1 year) field therapies such as efudex cream or PDT to forearms/wrists.
  9. * Planning to leave region in next 5 years
  10. * Subjects with allergies to xylocaine will be excluded if they need this topical anesthetic.

Contacts and Locations

Study Contact

Manager, Clinical Research Operations
CONTACT
937-245-7500
pturesearch@wrightstatephysicians.org
Regulatory Specialist
CONTACT
937-245-7500
pturesearch@wrightstatephysicians.org

Principal Investigator

Jeffrey Travers, MD, PhD
PRINCIPAL_INVESTIGATOR
Wright State University

Study Locations (Sites)

Wright State Physicians
Fairborn, Ohio, 45324
United States

Collaborators and Investigators

Sponsor: Wright State University

  • Jeffrey Travers, MD, PhD, PRINCIPAL_INVESTIGATOR, Wright State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-03-20
Study Completion Date2031-12

Study Record Updates

Study Start Date2024-03-20
Study Completion Date2031-12

Terms related to this study

Additional Relevant MeSH Terms

  • Actinic Keratoses
  • Aging
  • Non-Melanoma Skin Cancer