RECRUITING

First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy

Description

The goal of this clinical trial is to investigate the use of \[89Zr\]Zr-DFO-emapalumab as an IFN-γ PET imaging agent to detect lesions and response to therapy among treatment-naïve non-small cell lung cancer (NSCLC) patients. PET scans following the imaging agent will be completed prior to and about 30 days after starting immunotherapy.

Study Overview

Study Details

Study overview

The goal of this clinical trial is to investigate the use of \[89Zr\]Zr-DFO-emapalumab as an IFN-γ PET imaging agent to detect lesions and response to therapy among treatment-naïve non-small cell lung cancer (NSCLC) patients. PET scans following the imaging agent will be completed prior to and about 30 days after starting immunotherapy.

IFN-y PET Imaging: Bench to Bedside

First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy

Condition
Non Small Cell Lung Cancer
Intervention / Treatment

-

Contacts and Locations

Detroit

Karmanos Cancer Institute, Detroit, Michigan, United States, 48201

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    Nerissa T. Viola,

    Nerissa T Viola, PhD, PRINCIPAL_INVESTIGATOR, Barbara Ann Karmanos Cancer Institute

    Study Record Dates

    2027-06