RECRUITING

Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke

Description

The goal of this research study is to learn how the brain areas that plan and control movement interact with the areas responsible for hearing and perceiving speech in healthy adults and people who have had cerebellar strokes. The main questions it aims to answer are: 1. What regions of the brain's sensory systems show changes in their activity related to speech? 2. To what extent do these regions help listeners detect and correct speech errors? 3. What is the role of the cerebellum (a part of the brain in the back of the head) in these activities? Participants will be asked to complete several experimental sessions involving behavioral speech and related tests and non-invasive brain imaging using electroencephalography (EEG) and functional magnetic resonance imaging (fMRI).

Conditions

StrokeCerebellum
Talk to us

Related Conditions:

StrokeCerebellum

Study Overview

On this page

Study Details

Study overview

The goal of this research study is to learn how the brain areas that plan and control movement interact with the areas responsible for hearing and perceiving speech in healthy adults and people who have had cerebellar strokes. The main questions it aims to answer are: 1. What regions of the brain's sensory systems show changes in their activity related to speech? 2. To what extent do these regions help listeners detect and correct speech errors? 3. What is the role of the cerebellum (a part of the brain in the back of the head) in these activities? Participants will be asked to complete several experimental sessions involving behavioral speech and related tests and non-invasive brain imaging using electroencephalography (EEG) and functional magnetic resonance imaging (fMRI).

High-resolution Functional Imaging of Speech-induced Sensory Modulation

Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke

Condition
Stroke
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

University of Pittsburgh, Pittsburgh, Pennsylvania, United States, 15260

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18-49
  • * Right-handed
  • * Native English speaker
  • * Age 18 or older
  • * Right-handed
  • * Native English speaker
  • * History of cerebellar stroke
  • * Age 18 or older
  • * Right-handed
  • * Native English speaker
  • * Presence of MRI risk factors: metal and/or electromagnetic devices (e.g., pacemakers, neurostimulators) in the body, previous shrapnel injuries, use of an intrauterine device containing metal, claustrophobia, pregnant or possibly pregnant
  • * History of neurological / neurodegenerative disease or severe brain injury (e.g., stroke or severe traumatic brain injury)
  • * Hearing loss, defined by pure tone thresholds \>25 decibels (dB) hearing level (HL) at octave frequencies between 250-8000 Hz
  • * Clinical diagnosis and/or treatment for schizophrenia or other psychotic disorders
  • * Clinical diagnosis and/or treatment for neurocognitive disorders (e.g., dementia, delirium)
  • * Presence of a severe and unmanaged, clinically diagnosed attention disorder
  • * Clinically diagnosed with or treated for a speech, language, or hearing disorder
  • * Head circumference greater than 60cm or weight greater than 300 pounds
  • * History of severe claustrophobia
  • * Currently pregnant
  • * Presence of MRI risk factors: metal and/or electromagnetic devices (e.g., pacemakers, neurostimulators) in the body, previous shrapnel injuries, use of an intrauterine device containing metal, claustrophobia, pregnant or possibly pregnant
  • * History of neurological / neurodegenerative disease or severe brain injury other than stroke
  • * Hearing loss, defined by pure tone thresholds \>50 dB HL at octave frequencies between 250-4000 Hz
  • * Clinical diagnosis and/or treatment for schizophrenia or other psychotic disorders
  • * Clinical diagnosis and/or treatment for neurocognitive disorders (e.g., dementia, delirium)
  • * Presence of a severe and unmanaged, clinically diagnosed attention disorder
  • * Head circumference greater than 60cm or weight greater than 300 pounds
  • * History of severe claustrophobia
  • * Currently pregnant
  • * Presence of MRI risk factors: metal and/or electromagnetic devices (e.g., pacemakers, neurostimulators) in the body, previous shrapnel injuries, use of an intrauterine device containing metal, claustrophobia, pregnant or possibly pregnant
  • * History of neurological / neurodegenerative disease or severe brain injury (e.g., stroke or severe traumatic brain injury)
  • * Hearing loss, defined by pure tone thresholds \>50 dB HL at octave frequencies between 250-4000 Hz
  • * Clinical diagnosis and/or treatment for schizophrenia or other psychotic disorders
  • * Clinical diagnosis and/or treatment for neurocognitive disorders (e.g., dementia, delirium)
  • * Presence of a severe and unmanaged, clinically diagnosed attention disorder
  • * Clinically diagnosed with or treated for a speech, language, or hearing disorder
  • * Head circumference greater than 60cm or weight greater than 300 pounds
  • * History of severe claustrophobia
  • * Currently pregnant

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Pittsburgh,

Jason W Bohland, Ph.D., PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

2028-07