RECRUITING

Suicide Specific Rumination in Veterans

Description

Few treatments target core features of suicidal thoughts and behaviors in Veterans. Real-time functional magnetic resonance imaging neurofeedback can provide information regarding brain activation associated with suicide-specific rumination, defined as a "repetitive mental fixation on one's suicidal thoughts and intentions." The goal of this feasibility study is for Veterans to learn strategies for modulating activity within brain regions that have been demonstrated to contribute to the maintenance of rumination, as they receive neurofeedback feedback signals from the brain.

Study Overview

Study Details

Study overview

Few treatments target core features of suicidal thoughts and behaviors in Veterans. Real-time functional magnetic resonance imaging neurofeedback can provide information regarding brain activation associated with suicide-specific rumination, defined as a "repetitive mental fixation on one's suicidal thoughts and intentions." The goal of this feasibility study is for Veterans to learn strategies for modulating activity within brain regions that have been demonstrated to contribute to the maintenance of rumination, as they receive neurofeedback feedback signals from the brain.

Reducing Suicide-Specific Rumination in Veterans Using Real-time Functional Magnetic Resonance Imaging Neurofeedback

Suicide Specific Rumination in Veterans

Condition
Depression
Intervention / Treatment

-

Contacts and Locations

Bronx

James J. Peters VA Medical Center, Bronx, NY, Bronx, New York, United States, 10468-3904

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * U.S. military veteran between 18-65 years old
  • * past suicide attempt history
  • * negative pregnancy test on MRI scan days
  • * negative urine toxicology screen for drugs of abuse on MRI scan day
  • * score greater than or equal to 10 on the Suicide Rumination Scale
  • * clinically stabilized on psychotropic medications
  • * engaged in mental health care treatment
  • * able to provide written, informed consent
  • * no major medical or neurological disorders that could interfere with treatment
  • * moderate or severe traumatic brain injury
  • * current imminent suicide risk, as determined through psychiatric interview, responses to C-SSRS, and clinical judgment of the assessor
  • * any psychotic disorder
  • * MRI contraindications
  • * current substance use disorder
  • * pregnant or trying to become pregnant

Ages Eligible for Study

18 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

VA Office of Research and Development,

Philip R Szeszko, PhD, PRINCIPAL_INVESTIGATOR, James J. Peters Veterans Affairs Medical Center

Study Record Dates

2026-12-31