RECRUITING

Suicide Specific Rumination in Veterans

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Few treatments target core features of suicidal thoughts and behaviors in Veterans. Real-time functional magnetic resonance imaging neurofeedback can provide information regarding brain activation associated with suicide-specific rumination, defined as a "repetitive mental fixation on one's suicidal thoughts and intentions." The goal of this feasibility study is for Veterans to learn strategies for modulating activity within brain regions that have been demonstrated to contribute to the maintenance of rumination, as they receive neurofeedback feedback signals from the brain.

Official Title

Reducing Suicide-Specific Rumination in Veterans Using Real-time Functional Magnetic Resonance Imaging Neurofeedback

Quick Facts

Study Start:2024-08-01
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06481033

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * U.S. military veteran between 18-65 years old
  2. * past suicide attempt history
  3. * negative pregnancy test on MRI scan days
  4. * negative urine toxicology screen for drugs of abuse on MRI scan day
  5. * score greater than or equal to 10 on the Suicide Rumination Scale
  6. * clinically stabilized on psychotropic medications
  7. * engaged in mental health care treatment
  8. * able to provide written, informed consent
  1. * no major medical or neurological disorders that could interfere with treatment
  2. * moderate or severe traumatic brain injury
  3. * current imminent suicide risk, as determined through psychiatric interview, responses to C-SSRS, and clinical judgment of the assessor
  4. * any psychotic disorder
  5. * MRI contraindications
  6. * current substance use disorder
  7. * pregnant or trying to become pregnant

Contacts and Locations

Study Contact

Philip R Szeszko, PhD
CONTACT
(718) 584-9000
Philip.Szeszko@va.gov

Principal Investigator

Philip R Szeszko, PhD
PRINCIPAL_INVESTIGATOR
James J. Peters Veterans Affairs Medical Center

Study Locations (Sites)

James J. Peters VA Medical Center, Bronx, NY
Bronx, New York, 10468-3904
United States

Collaborators and Investigators

Sponsor: VA Office of Research and Development

  • Philip R Szeszko, PhD, PRINCIPAL_INVESTIGATOR, James J. Peters Veterans Affairs Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-08-01
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2024-08-01
Study Completion Date2026-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Depression
  • Suicide
  • Mood Disorders