RECRUITING

Preoperative Use of Pantoprazole for Prevention of Post Operative Nausea and Vomiting in Gynecologic Surgery

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to see if pantoprazole (a proton pump inhibitor used for acid reflux/heart burn) can reduce nausea and vomiting after gynecologic surgery in women between the ages of 18 and 79. Researchers will compare a placebo to the active medication. Participants will be asked to take three pills around their surgery, two taken before and one taken the night after.

Official Title

Preoperative Use of Pantoprazole for Prevention of Post Operative Nausea and Vomiting in Gynecologic Surgery

Quick Facts

Study Start:2022-08-26
Study Completion:2025-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06488001

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 79 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Undergoing elective gynecological surgery by either an open abdominal or minimally invasive approach (to include both endoscopic and vaginal). Procedure must be performed under general anesthesia.
  1. * Pregnant,
  2. * Patients with gastrointestinal disease requiring ongoing medical management.
  3. * Prior gastrointestinal surgery with the exception of diagnostic procedures, appendectomy and cholecystectomy.
  4. * Patients with a history of H2 receptor blocker use, proton pump inhibitor use or other GERD specific therapy within 30 days of surgery.
  5. * Any patient identified by their surgical care team as having a history of PONV warranting additional perioperative prophylaxis.
  6. * Known r suspected malignancy
  7. * Lactose intolerance

Contacts and Locations

Study Contact

Casey Timmerman, DO
CONTACT
757-953-7767
casey.j.timmerman2.mil@health.mil
Melissa Infosino, MD
CONTACT
Melissa.R.Infosino.mil@health.mil

Study Locations (Sites)

Naval Medical Center Portsmouth
Portsmouth, Virginia, 23708
United States

Collaborators and Investigators

Sponsor: United States Naval Medical Center, Portsmouth

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-08-26
Study Completion Date2025-03

Study Record Updates

Study Start Date2022-08-26
Study Completion Date2025-03

Terms related to this study

Keywords Provided by Researchers

  • PONV
  • Postoperative nausea

Additional Relevant MeSH Terms

  • Postoperative Nausea and Vomiting